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Research Software
Utility Software
Software for Research
Software in this section is focused on a specific research goal. Most
have been described in greater detail in one of our publications.
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GoFish!.
This program (available as a Java applet) allows the user to select a
subset of Gene Ontology (GO) attributes, and ranks genes according to
the probability of having all those attributes. It can also be
downloaded, with source code, as a jar file; click
here.
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ClusterJudge.
Not sure which clustering algorithm to use with your gene expression
data? ClusterJudge scores the results from any clustering algorithm,
using existing annotation, so you can see which one best groups genes
by function.
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Complexpander.
A wealth of information is now available on interactions between pairs
of proteins. Complexpander
uses Bayes' Rule to combine interaction information
from several sources to predict protein complexes.
Results are generated in both graphical and tabular form.
Predicted interaction networks may be exported to several network-analysis tools,
for further examination.
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Here's the new, improved
ChIPper,
a tool for analysis of ChIP2 data.
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FuncAssociate.
This program takes a list of genes as input and produces a ranked
list of the Gene Ontology
attributes that the input list is enriched (or depleted) for.
To download the source click
here.
A new version of
FuncAssociate (still at the beta stage!) is now available. This version
supports a wider range of naming schemes for input genes, and uses more
frequently updated GO associations. However, some features of the original
version, such as sorting by LOD or the option to see the gene-attribute table,
are not yet implemented.
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SILVER
produces visual and numerical output to aid in protein-sequence
determination from tandem mass spectrometry. You can access SILVER
through a web
interface or you can download the Python code for it. The software is free of charge,
but you must sign our license agreement.
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BioGraphNet is a common
standard and collection of services for sharing distributed network
information. We provide tools that enable scientists to make their
interaction data available through web-services with a minimum of
work. In addition, we serve several network data types, and encourage
others to participate, using objects we have registered in
BioMOBY's
ontology.
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BioTrawler is an
example application that builds on the interaction services provided
using BioGraphNet to
dynamically discover suitable distributed data sources for biological
networks, integrate those you select 'just in time', and visualize a
graph comprising a user-defined set of genes and their neighbors.
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Query Chem is a Web program that
integrates chemical structure and text-based searching using publicly available chemical databases
and Google's Web Application Program Interface (API). Query Chem makes it
possible to search the Web for information about chemical structures without knowing their common
names or identifiers. Query Chem's search results can retrieve many interesting
structure-property relationships of biomolecules on the Web.
Utility Software
Software in this section has a more utilitarian bias to it. These programs are often not
associated with any given project, but some are used silently 'behind
the scenes' in several projects. We provide them 'as-is', and while we
will be happy to answer short questions, we regret we cannot provide
detailed or ongoing support. We welcome comments, suggestions, raves,
and chocolate.
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Yorfeus
automatically downloads the Saccharomyces Genome Databse (SGD) tables
mapping common gene names, ORFs, SGD IDs, and their aliases to each other.
It provides an easy command-line interface for looking up information,
for human users or other programs. It's always up-to-date.
You can download Yorfeus here.
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qqsub is a
wrapper to the PBS queuing system, designed to make submitting jobs more convenient. It
makes good on several perceived shortcomings of OpenPBS, to make the
batch-queuing system as transparent as possible, particularly for
novice users.
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Our Synergizer project aims to catalog synonymous identifiers for genes and
proteins.
synergizer/translate is a a web interface to the
Synergizer database that allows users to translate gene names from one
naming scheme ("namespace") to another. For more information about
the Synergizer, please vist the Synergizer
page.
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