Yfunc lets you browse current and predicted gene functions in yeast

Enter a GO term ID (example: GO:0003723):
Enter a yeast gene name to browse (example:AIR1):

  Prediction of "CLA4"

Common name: CLA4
Systematic Name: YNL298W
SGD_ID: S000005242
Feature type: verified
Feature description: Cdc42p activated signal transducing kinase of the PAK(p21-activated kinase) family, involved inseptin ring assembly and cytokinesis; directlyphosphorylates septins Cdc3p and Cdc10p; otheryeast PAK family members are Ste20p and Skm1p

* the highlighted genes are those "interesting" predictions that
(1) are not currently annotated to this function,
(2) are not annotated with any ancestor GO terms (except the root term),
(3) have a projected precision score > 05
Histogram of scores for current annotations (annotated with the target function),
and novel predictions (not annotated with the target function)
Histogram of scores for current annotations, and predictions
GO_IDGO descriptionGO branchcurrent annotationprediction scoreprojected precisionGO:0016772transferase activity, transferring phosphorus-containing groupsMF&radic0.899791 GO:0016301kinase activityMF&radic0.855891 GO:0004672protein kinase activityMF&radic0.842121 GO:0016773phosphotransferase activity, alcohol group as acceptorMF&radic0.844921 GO:0007096regulation of exit from mitosisBP&radic0.50750.96153 GO:0007088regulation of mitosisBP&radic0.653620.95833 GO:0051726regulation of cell cycleBP&radic0.813320.95833 GO:0000074regulation of progression through cell cycleBP&radic0.813320.95833 GO:0051301cell divisionBP&radic0.787060.95652 GO:0000910cytokinesisBP&radic0.633970.95102 GO:0006468protein amino acid phosphorylationBP&radic0.580720.94047 GO:0006796phosphate metabolismBP&radic0.751720.93975 GO:0006793phosphorus metabolismBP&radic0.751720.93975 GO:0007067mitosisBP&radic0.753910.93975 GO:0000087M phase of mitotic cell cycleBP&radic0.747340.93888 GO:0016310phosphorylationBP&radic0.745570.93867 GO:0030467establishment and/or maintenance of cell polarity (sensu Fungi)BP&radic0.731890.93455 GO:0007163establishment and/or maintenance of cell polarityBP&radic0.731890.93455 GO:0030468establishment of cell polarity (sensu Fungi)BP&radic0.728730.93455 GO:0030010establishment of cell polarityBP&radic0.728730.93455 GO:0004674protein serine/threonine kinase activityMF&radic0.395680.93376 GO:0007105cytokinesis, site selectionBP 0.575130.92791 GO:0000282bud site selectionBP 0.575130.92791 GO:0007266Rho protein signal transductionBP&radic0.380560.92364 GO:0007166cell surface receptor linked signal transductionBP 0.553670.92029 GO:0000278mitotic cell cycleBP&radic0.687670.91867 GO:0005933budCC 0.557460.91814 GO:0031137regulation of conjugation with cellular fusionBP 0.379190.91704 GO:0032005signal transduction during conjugation with cellular fusionBP 0.379190.91704 GO:0000750pheromone-dependent signal transduction during conjugation with cellular fusionBP 0.379190.91704 GO:0046999regulation of conjugationBP 0.379190.91704 GO:0007186G-protein coupled receptor protein signaling pathwayBP 0.369490.91517 GO:0007124pseudohyphal growthBP 0.54290.91304 GO:0000003reproductionBP&radic0.668910.9111 GO:0000279M phaseBP&radic0.664660.91065 GO:0030427site of polarized growthCC 0.541240.91061 GO:0001403invasive growth (sensu Saccharomyces)BP 0.525420.90858 GO:0007264small GTPase mediated signal transductionBP&radic0.523320.90849 GO:0000902cell morphogenesisBP&radic0.65550.90823 GO:0048856anatomical structure developmentBP&radic0.65550.90823 GO:0009653morphogenesisBP&radic0.65550.90823 GO:0000749response to pheromone during conjugation with cellular fusionBP 0.522670.90819 GO:0016049cell growthBP 0.521610.90465 GO:0044463cell projection partCC 0.434960.90116 GO:0019954asexual reproductionBP&radic0.519410.89989 GO:0007114cell buddingBP&radic0.519410.89989 GO:0040007growthBP&radic0.647990.89954 GO:0007165signal transductionBP&radic0.648410.89954 GO:0007154cell communicationBP&radic0.634520.89192 GO:0042995cell projectionCC 0.422510.89088 GO:0005937mating projectionCC 0.422510.89088 GO:0030447filamentous growthBP 0.492520.88666 GO:0019236response to pheromoneBP 0.489610.88408 GO:0043332mating projection tipCC 0.403770.88375 GO:0000747conjugation with cellular fusionBP 0.616580.88002 GO:0019953sexual reproductionBP 0.616580.88002 GO:0000746conjugationBP 0.616580.88002 GO:0030695GTPase regulator activityMF 0.265540.87985 GO:0005083small GTPase regulator activityMF 0.256360.87682 GO:0000131incipient bud siteCC 0.381660.87622 GO:0008361regulation of cell sizeBP 0.597050.86929 GO:0050876reproductive physiological processBP 0.592320.86686 GO:0048610reproductive cellular physiological processBP 0.592320.86686 GO:0051704interaction between organismsBP 0.592110.86682 GO:0005935bud neckCC 0.426770.86426 GO:0007242intracellular signaling cascadeBP&radic0.579430.86106 GO:0042221response to chemical stimulusBP 0.555890.84361 GO:0030234enzyme regulator activityMF 0.225760.82984 GO:0005934bud tipCC 0.269750.82645 GO:0007010cytoskeleton organization and biogenesisBP 0.497860.8126 GO:0007120axial bud site selectionBP 0.24650.80088 GO:0044430cytoskeletal partCC&radic0.284180.75454 GO:0005856cytoskeletonCC&radic0.274030.74185 GO:0030036actin cytoskeleton organization and biogenesisBP 0.393820.74092 GO:0030029actin filament-based processBP 0.385010.73332 GO:0048590non-developmental growthBP&radic0.262960.72554 GO:0007117budding cell bud growthBP&radic0.262960.72554 GO:0015629actin cytoskeletonCC&radic0.18190.72091 GO:0008289lipid bindingMF 0.119580.71781 GO:0035091phosphoinositide bindingMF 0.072020.71737 GO:0030863cortical cytoskeletonCC&radic0.178130.71571 GO:0030864cortical actin cytoskeletonCC&radic0.178130.71571 GO:0005886plasma membraneCC 0.249990.71528 GO:0004871signal transducer activityMF 0.113850.70703 GO:0044448cell cortex partCC&radic0.167370.69673 GO:0000267cell fractionCC 0.233240.69381 GO:0046903secretionBP 0.346470.68755 GO:0005543phospholipid bindingMF 0.09970.68334 GO:0007015actin filament organizationBP 0.223750.68278 GO:0005938cell cortexCC&radic0.154790.67904 GO:0000075cell cycle checkpointBP 0.214550.67008 GO:0045011actin cable formationBP 0.065820.65749 GO:0051017actin filament bundle formationBP 0.065820.65749 GO:0006970response to osmotic stressBP 0.20660.65728 GO:0051325interphaseBP 0.184150.6287 GO:0051329interphase of mitotic cell cycleBP 0.184150.6287 GO:0000086G2/M transition of mitotic cell cycleBP 0.099450.61668 GO:0000753cellular morphogenesis during conjugation with cellular fusionBP 0.097080.61299 GO:0032200telomere organization and biogenesisBP 0.28090.61052 GO:0000723telomere maintenanceBP 0.28090.61052 GO:0045045secretory pathwayBP 0.268720.59539 GO:0000767cellular morphogenesis during conjugationBP 0.088920.59535 GO:0009628response to abiotic stimulusBP 0.258520.58184 GO:0000226microtubule cytoskeleton organization and biogenesisBP 0.147350.57355 GO:0006897endocytosisBP 0.145470.57137 GO:0007017microtubule-based processBP 0.132110.55056 GO:0005057receptor signaling protein activityMF 0.033140.54537 GO:0007047cell wall organization and biogenesisBP 0.226050.5376 GO:0045229external encapsulating structure organization and biogenesisBP 0.226050.5376 GO:0000135septin checkpointBP 0.033480.53183 GO:0012505endomembrane systemCC 0.130840.51879 GO:0004681casein kinase I activityMF 0.025870.51485 GO:0030478actin capCC&radic0.053830.50531 GO:0045859regulation of protein kinase activityBP 0.050410.49169 GO:0051338regulation of transferase activityBP 0.050410.49169 GO:0043549regulation of kinase activityBP 0.050410.49169 GO:0006887exocytosisBP 0.103030.48912 GO:0031106septin ring organizationBP 0.025650.48727 GO:0000921septin ring assemblyBP 0.025650.48727 GO:0032185septin cytoskeleton organization and biogenesisBP 0.025650.48727 GO:0000922spindle poleCC 0.065660.48585 GO:0051321meiotic cell cycleBP 0.192020.48262 GO:0007126meiosisBP 0.192020.48262 GO:0051327M phase of meiotic cell cycleBP 0.192020.48262 GO:0048308organelle inheritanceBP 0.093070.46481 GO:0048523negative regulation of cellular processBP 0.180010.46315 GO:0051243negative regulation of cellular physiological processBP 0.180010.46315 GO:0007121bipolar bud site selectionBP 0.09120.45906 GO:0007033vacuole organization and biogenesisBP 0.090650.4578 GO:0044432endoplasmic reticulum partCC 0.102860.45209 GO:0004702receptor signaling protein serine/threonine kinase activityMF 0.020330.44787 GO:0048519negative regulation of biological processBP 0.170750.44663 GO:0006403RNA localizationBP 0.086270.44438 GO:0044264cellular polysaccharide metabolismBP 0.086040.44301 GO:0005976polysaccharide metabolismBP 0.086040.44301 GO:0005624membrane fractionCC 0.051750.44048 GO:0048311mitochondrion distributionBP 0.038410.43511 GO:0051646mitochondrion localizationBP 0.038410.43511 GO:0000001mitochondrion inheritanceBP 0.038410.43511 GO:0000011vacuole inheritanceBP 0.038250.43325 GO:0006357regulation of transcription from RNA polymerase II promoterBP 0.160910.4293 GO:0050790regulation of catalytic activityBP 0.079160.42169 GO:0005789endoplasmic reticulum membraneCC 0.089140.41148 GO:0000920cell separation during cytokinesisBP 0.016140.40206 GO:0007243protein kinase cascadeBP 0.032540.40192 GO:0040020regulation of meiosisBP 0.032560.40192 GO:0006261DNA-dependent DNA replicationBP 0.069880.3926 GO:0051640organelle localizationBP 0.069870.3926 GO:0004693cyclin-dependent protein kinase activityMF 0.013930.39142 GO:0042175nuclear envelope-endoplasmic reticulum networkCC 0.082860.38946 GO:0008298intracellular mRNA localizationBP 0.015030.38415 GO:0045033peroxisome inheritanceBP 0.014790.38352 GO:0006260DNA replicationBP 0.136890.38349 GO:0051128regulation of cell organization and biogenesisBP 0.028550.37895 GO:0044255cellular lipid metabolismBP 0.133640.37701 GO:0004680casein kinase activityMF 0.01290.37447 GO:0005840ribosomeCC 0.078790.37391 GO:0019887protein kinase regulator activityMF 0.023460.37027 GO:0044459plasma membrane partCC 0.035350.36436 GO:0051656establishment of organelle localizationBP 0.026460.36351 GO:0016538cyclin-dependent protein kinase regulator activityMF 0.013190.36135 GO:0043285biopolymer catabolismBP 0.125340.36026 GO:0006893Golgi to plasma membrane transportBP 0.025180.35559 GO:0005975carbohydrate metabolismBP 0.122520.35459 GO:0004709MAP kinase kinase kinase activityMF 0.011740.35159 GO:0009719response to endogenous stimulusBP 0.120550.35018 GO:0007118budding cell apical bud growthBP&radic0.02440.34945 GO:0005819spindleCC 0.032670.34821 GO:0043118negative regulation of physiological processBP 0.119380.34741 GO:0005816spindle pole bodyCC 0.032320.34526 GO:0005815microtubule organizing centerCC 0.032320.34526 GO:0006629lipid metabolismBP 0.117470.34365 GO:0007531mating type determinationBP 0.023420.34217 GO:0007530sex determinationBP 0.023420.34217 GO:0000082G1/S transition of mitotic cell cycleBP 0.055620.34185 GO:0007119budding cell isotropic bud growthBP 0.010730.33727 GO:0031382mating projection biogenesisBP 0.010460.33594 GO:0030031cell projection biogenesisBP 0.009990.33089 GO:0030030cell projection organization and biogenesisBP 0.009990.33089 GO:0045893positive regulation of transcription, DNA-dependentBP 0.052620.32948 GO:0044445cytosolic partCC 0.065880.32794 GO:0048193Golgi vesicle transportBP 0.109950.32657 GO:0051242positive regulation of cellular physiological processBP 0.109740.32625 GO:0048522positive regulation of cellular processBP 0.109740.32625 GO:0043119positive regulation of physiological processBP 0.109740.32625 GO:0044265cellular macromolecule catabolismBP 0.108270.32295 GO:0007005mitochondrion organization and biogenesisBP 0.108240.32279 GO:0043632modification-dependent macromolecule catabolismBP 0.107550.32103 GO:0000079regulation of cyclin-dependent protein kinase activityBP 0.02110.3208 GO:0030466chromatin silencing at silent mating-type cassetteBP 0.020780.31723 GO:0005773vacuoleCC 0.061180.30708 GO:0051052regulation of DNA metabolismBP 0.019610.30556 GO:0016817hydrolase activity, acting on acid anhydridesMF 0.019880.30422 GO:0016818hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesMF 0.019880.30422 GO:0003677DNA bindingMF 0.01990.30422 GO:0016462pyrophosphatase activityMF 0.019880.30422 GO:0005830cytosolic ribosome (sensu Eukaryota)CC 0.060040.3018 GO:0009893positive regulation of metabolismBP 0.046550.29964 GO:0031325positive regulation of cellular metabolismBP 0.046550.29964 GO:0030435sporulationBP 0.09820.29795 GO:0031383regulation of mating projection biogenesisBP 0.007320.29344 GO:0031344regulation of cell projection organization and biogenesisBP 0.007320.29344 GO:0008092cytoskeletal protein bindingMF 0.014680.29261 GO:0004872receptor activityMF 0.008790.29066 GO:0007534gene conversion at mating-type locusBP 0.01820.28794 GO:0008104protein localizationBP 0.094260.28762 GO:0045935positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismBP 0.043740.28511 GO:0007533mating type switchingBP 0.017840.28341 GO:0031385regulation of termination of mating projection growthBP 0.006920.28281 GO:0015630microtubule cytoskeletonCC 0.055570.28224 GO:0019207kinase regulator activityMF 0.013780.28107 GO:0004888transmembrane receptor activityMF 0.00810.27913 GO:0045184establishment of protein localizationBP 0.089680.27516 GO:0009892negative regulation of metabolismBP 0.089270.27408 GO:0031384regulation of initiation of mating projection growthBP 0.006630.27339 GO:0007064mitotic sister chromatid cohesionBP 0.016930.27109 GO:0007062sister chromatid cohesionBP 0.016830.27072 GO:0008154actin polymerization and/or depolymerizationBP 0.006290.26613 GO:0004712protein threonine/tyrosine kinase activityMF 0.006760.26331 GO:0048518positive regulation of biological processBP 0.084520.26167 GO:0006888ER to Golgi vesicle-mediated transportBP 0.038540.25943 GO:0003735structural constituent of ribosomeMF 0.017240.25622 GO:0044262cellular carbohydrate metabolismBP 0.081370.25262 GO:0017111nucleoside-triphosphatase activityMF 0.016930.25259 GO:0016051carbohydrate biosynthesisBP 0.036960.25091 GO:0000228nuclear chromosomeCC 0.047080.2506 GO:0005694chromosomeCC 0.046060.2466 GO:0008156negative regulation of DNA replicationBP 0.005560.24365 GO:0051049regulation of transportBP 0.005530.24091 GO:0006310DNA recombinationBP 0.076970.2408 GO:0045944positive regulation of transcription from RNA polymerase II promoterBP 0.035130.24009 GO:0045941positive regulation of transcriptionBP 0.035020.23973 GO:0006275regulation of DNA replicationBP 0.014620.23918 GO:0007046ribosome biogenesisBP 0.075870.23764 GO:0006974response to DNA damage stimulusBP 0.075460.23661 GO:0005794Golgi apparatusCC 0.043280.2356 GO:0006270DNA replication initiationBP 0.014350.23499 GO:0005519cytoskeletal regulatory protein bindingMF 0.005490.23436 GO:0000322storage vacuoleCC 0.042730.23328 GO:0000323lytic vacuoleCC 0.042730.23328 GO:0000324vacuole (sensu Fungi)CC 0.042730.23328 GO:0030705cytoskeleton-dependent intracellular transportBP 0.014170.23271 GO:0030163protein catabolismBP 0.072280.22802 GO:0000132establishment of mitotic spindle orientationBP 0.005130.22624 GO:0051294establishment of spindle orientationBP 0.005130.22624 GO:0051653spindle localizationBP 0.005130.22624 GO:0051293establishment of spindle localizationBP 0.005130.22624 GO:0040001establishment of mitotic spindle localizationBP 0.005130.22624 GO:0030174regulation of DNA replication initiationBP 0.005090.22493 GO:0005618cell wallCC 0.017290.22419 GO:0030312external encapsulating structureCC 0.017290.22419 GO:0009277cell wall (sensu Fungi)CC 0.017290.22419 GO:0006038cell wall chitin biosynthesisBP 0.005060.22354 GO:0016021integral to membraneCC 0.040380.2222 GO:0000271polysaccharide biosynthesisBP 0.031920.22178 GO:0043284biopolymer biosynthesisBP 0.031920.22178 GO:0000076DNA replication checkpointBP 0.004970.22094 GO:0032297negative regulation of DNA replication initiationBP 0.004970.22094 GO:0004708MAP kinase kinase activityMF 0.005190.22091 GO:0051169nuclear transportBP 0.069270.21963 GO:0051320S phaseBP 0.004910.21743 GO:0000084S phase of mitotic cell cycleBP 0.004910.21743 GO:0009651response to salt stressBP 0.0130.21575 GO:0045934negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolismBP 0.067660.21518 GO:0044257cellular protein catabolismBP 0.067160.21367 GO:0044454nuclear chromosome partCC 0.03840.21335 GO:0006508proteolysisBP 0.066410.21153 GO:0006913nucleocytoplasmic transportBP 0.066390.21152 GO:0043161proteasomal ubiquitin-dependent protein catabolismBP 0.030040.20942 GO:0031324negative regulation of cellular metabolismBP 0.065510.20905 GO:0051603proteolysis during cellular protein catabolismBP 0.065370.20876 GO:0016757transferase activity, transferring glycosyl groupsMF 0.008450.20662 GO:0031505cell wall organization and biogenesis (sensu Fungi)BP 0.029510.20645 GO:0005625soluble fractionCC 0.015850.20524 GO:0005034osmosensor activityMF 0.004160.20356 GO:0044437vacuolar partCC 0.036360.20289 GO:0006325establishment and/or maintenance of chromatin architectureBP 0.062780.20129 GO:0006323DNA packagingBP 0.062780.20129 GO:0005085guanyl-nucleotide exchange factor activityMF 0.004610.20048 GO:0031988membrane-bound vesicleCC 0.035790.19919 GO:0031410cytoplasmic vesicleCC 0.035790.19919 GO:0016023cytoplasmic membrane-bound vesicleCC 0.035790.19919 GO:0016568chromatin modificationBP 0.062110.19917 GO:0000165MAPKKK cascadeBP 0.011730.19805 GO:0007031peroxisome organization and biogenesisBP 0.028040.19742 GO:0006511ubiquitin-dependent protein catabolismBP 0.061550.19733 GO:0019941modification-dependent protein catabolismBP 0.061550.19733 GO:0008047enzyme activator activityMF 0.007880.1972 GO:0016481negative regulation of transcriptionBP 0.061320.19666 GO:0003723RNA bindingMF 0.014260.19584 GO:0031497chromatin assemblyBP 0.027790.19582 GO:0016283eukaryotic 48S initiation complexCC 0.015030.19527 GO:0005843cytosolic small ribosomal subunit (sensu Eukaryota)CC 0.015030.19527 GO:0044427chromosomal partCC 0.034940.19472 GO:0006886intracellular protein transportBP 0.060390.19409 GO:0000790nuclear chromatinCC 0.014920.19381 GO:0015935small ribosomal subunitCC 0.014830.19293 GO:0006281DNA repairBP 0.059870.19264 GO:0031509telomeric heterochromatin formationBP 0.02730.19253 GO:0006348chromatin silencing at telomereBP 0.02730.19253 GO:0007231osmosensory signaling pathwayBP 0.011320.19245 GO:0040029regulation of gene expression, epigeneticBP 0.027220.19222 GO:0005774vacuolar membraneCC 0.03430.19149 GO:0000030mannosyltransferase activityMF 0.007520.19111 GO:0031982vesicleCC 0.034050.18978 GO:0006914autophagyBP 0.026720.18882 GO:0031226intrinsic to plasma membraneCC 0.014510.18751 GO:0009272cell wall biosynthesis (sensu Fungi)BP 0.01090.18682 GO:0042546cell wall biosynthesisBP 0.01090.18682 GO:0000329vacuolar membrane (sensu Fungi)CC 0.014340.18639 GO:0007127meiosis IBP 0.026290.18594 GO:0006312mitotic recombinationBP 0.026070.18439 GO:0006807nitrogen compound metabolismBP 0.05690.1833 GO:0000793condensed chromosomeCC 0.0140.18127 GO:0031507heterochromatin formationBP 0.025480.18053 GO:0016458gene silencingBP 0.025480.18053 GO:0006342chromatin silencingBP 0.025480.18053 GO:0045814negative regulation of gene expression, epigeneticBP 0.025480.18053 GO:0006461protein complex assemblyBP 0.055660.18004 GO:0006037cell wall chitin metabolismBP 0.004030.17975 GO:0004696glycogen synthase kinase 3 activityMF 0.003290.1793 GO:0016585chromatin remodeling complexCC 0.013780.17825 GO:0051278cell wall polysaccharide biosynthesis (sensu Fungi)BP 0.010080.17562 GO:0007059chromosome segregationBP 0.053730.17482 GO:0006892post-Golgi vesicle-mediated transportBP 0.024540.17374 GO:0003887DNA-directed DNA polymerase activityMF 0.003640.17322 GO:0016788hydrolase activity, acting on ester bondsMF 0.012870.17274 GO:0000819sister chromatid segregationBP 0.024410.17271 GO:0032156septin cytoskeletonCC 0.008830.17182 GO:0005940septin ringCC 0.008830.17182 GO:0000794condensed nuclear chromosomeCC 0.01320.16986 GO:0000785chromatinCC 0.013070.16794 GO:0030154cell differentiationBP 0.051330.16754 GO:0009308amine metabolismBP 0.051080.1666 GO:0000070mitotic sister chromatid segregationBP 0.023470.16586 GO:0016758transferase activity, transferring hexosyl groupsMF 0.006230.16563 GO:0003779actin bindingMF 0.003380.16453 GO:0030295protein kinase activator activityMF 0.002760.16355 GO:0030134ER to Golgi transport vesicleCC 0.008640.16311 GO:0019752carboxylic acid metabolismBP 0.049750.16291 GO:0006082organic acid metabolismBP 0.049750.16291 GO:0006338chromatin remodelingBP 0.049630.16255 GO:0016567protein ubiquitinationBP 0.022790.16155 GO:0016563transcriptional activator activityMF 0.006120.16123 GO:0031224intrinsic to membraneCC 0.029470.161 GO:0042273ribosomal large subunit biogenesisBP 0.009170.161 GO:0045892negative regulation of transcription, DNA-dependentBP 0.048950.16033 GO:0006512ubiquitin cycleBP 0.022620.16023 GO:0008415acyltransferase activityMF 0.005890.15796 GO:0016747transferase activity, transferring groups other than amino-acyl groupsMF 0.005890.15796 GO:0009605response to external stimulusBP 0.008940.15684 GO:0009991response to extracellular stimulusBP 0.008940.15684 GO:0031667response to nutrient levelsBP 0.008940.15684 GO:0030554adenyl nucleotide bindingMF 0.00310.1561 GO:0007051spindle organization and biogenesisBP 0.021980.15589 GO:0005875microtubule associated complexCC 0.012250.15502 GO:0005842cytosolic large ribosomal subunit (sensu Eukaryota)CC 0.012120.15349 GO:0000725recombinational repairBP 0.008660.15277 GO:0000776kinetochoreCC 0.011990.15192 GO:0015031protein transportBP 0.046360.15189 GO:0032446protein modification by small protein conjugationBP 0.021340.15171 GO:0006333chromatin assembly or disassemblyBP 0.046120.15126 GO:0044431Golgi apparatus partCC 0.027910.14961 GO:0051053negative regulation of DNA metabolismBP 0.00840.14895 GO:0005730nucleolusCC 0.02740.14659 GO:0006302double-strand break repairBP 0.020530.14596 GO:0003774motor activityMF 0.00280.14469 GO:0006044N-acetylglucosamine metabolismBP 0.008130.14464 GO:0006040amino sugar metabolismBP 0.008130.14464 GO:0006041glucosamine metabolismBP 0.008130.14464 GO:0006605protein targetingBP 0.044020.14458 GO:0046349amino sugar biosynthesisBP 0.008090.14409 GO:0006042glucosamine biosynthesisBP 0.008090.14409 GO:0006045N-acetylglucosamine biosynthesisBP 0.008090.14409 GO:0006311meiotic gene conversionBP 0.008080.14397 GO:0050801ion homeostasisBP 0.04360.14332 GO:0007131meiotic recombinationBP 0.019680.14005 GO:0006644phospholipid metabolismBP 0.019490.13893 GO:0016282eukaryotic 43S preinitiation complexCC 0.011080.13858 GO:0000724double-strand break repair via homologous recombinationBP 0.007640.13726 GO:0003924GTPase activityMF 0.005060.13667 GO:0048622reproductive sporulationBP 0.041160.13537 GO:0030437sporulation (sensu Fungi)BP 0.041160.13537 GO:0008380RNA splicingBP 0.040930.13468 GO:0042592homeostasisBP 0.04090.13461 GO:0045910negative regulation of DNA recombinationBP 0.002860.13428 GO:0000775chromosome, pericentric regionCC 0.010760.13342 GO:0006031chitin biosynthesisBP 0.007360.13244 GO:0000123histone acetyltransferase complexCC 0.010610.13168 GO:0016410N-acyltransferase activityMF 0.004880.13122 GO:0019209kinase activator activityMF 0.001970.13047 GO:0006623protein targeting to vacuoleBP 0.018320.13026 GO:0003682chromatin bindingMF 0.002480.13007 GO:0000018regulation of DNA recombinationBP 0.007220.12997 GO:0000754adaptation to pheromone during conjugation with cellular fusionBP 0.007250.12997 GO:0007234osmosensory signaling pathway via two-component systemBP 0.007220.12997 GO:0000160two-component signal transduction system (phosphorelay)BP 0.007220.12997 GO:0008168methyltransferase activityMF 0.004770.12744 GO:0006643membrane lipid metabolismBP 0.038740.12743 GO:0017076purine nucleotide bindingMF 0.004740.12735 GO:0043248proteasome assemblyBP 0.002680.12653 GO:0016746transferase activity, transferring acyl groupsMF 0.010260.12496 GO:0005798Golgi-associated vesicleCC 0.010030.12324 GO:0000778condensed nuclear chromosome kinetochoreCC 0.010020.12324 GO:0000777condensed chromosome kinetochoreCC 0.010020.12324 GO:0004518nuclease activityMF 0.004610.1232 GO:0005635nuclear envelopeCC 0.022840.12198 GO:0006457protein foldingBP 0.017180.12179 GO:0006267pre-replicative complex formation and maintenanceBP 0.006560.11868 GO:0030476spore wall assembly (sensu Fungi)BP 0.016740.11865 GO:0042244spore wall assemblyBP 0.016740.11865 GO:0000139Golgi membraneCC 0.009650.11767 GO:0031461cullin-RING ubiquitin ligase complexCC 0.003040.11709 GO:0019005SCF ubiquitin ligase complexCC 0.003040.11709 GO:0001402signal transduction during filamentous growthBP 0.002420.11639 GO:0030133transport vesicleCC 0.00950.11569 GO:0007584response to nutrientBP 0.006310.11452 GO:0006313transposition, DNA-mediatedBP 0.002370.11449 GO:0000335negative regulation of DNA transpositionBP 0.002370.11449 GO:0000337regulation of DNA transpositionBP 0.002370.11449 GO:0005667transcription factor complexCC 0.021510.11429 GO:0016741transferase activity, transferring one-carbon groupsMF 0.004330.11391 GO:0007568agingBP 0.016090.11377 GO:0007052mitotic spindle organization and biogenesisBP 0.016060.11356 GO:0007569cell agingBP 0.015920.11239 GO:0051015actin filament bindingMF 0.001540.11222 GO:0042162telomeric DNA bindingMF 0.001540.11222 GO:0045003double-strand break repair via synthesis-dependent strand annealingBP 0.006110.1112 GO:0019725cell homeostasisBP 0.033370.10975 GO:0030135coated vesicleCC 0.009110.10965 GO:0032196transpositionBP 0.002240.10959 GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolismBP 0.002240.10917 GO:0032155cell division site partCC 0.005250.10809 GO:0032153cell division siteCC 0.005250.10809 GO:0006873cell ion homeostasisBP 0.032750.10784 GO:0005996monosaccharide metabolismBP 0.015090.10646 GO:0043543protein amino acid acylationBP 0.015020.10599 GO:0045132meiotic chromosome segregationBP 0.005830.10563 GO:0051168nuclear exportBP 0.014950.10551 GO:0006812cation transportBP 0.014940.10529 GO:0007030Golgi organization and biogenesisBP 0.002120.10431 GO:0006273lagging strand elongationBP 0.005760.10394 GO:0005200structural constituent of cytoskeletonMF 0.004020.10321 GO:0016570histone modificationBP 0.014580.10289 GO:0016569covalent chromatin modificationBP 0.014580.10289 GO:0006473protein amino acid acetylationBP 0.014560.10281 GO:0007107membrane addition at site of cytokinesisBP 0.002090.10258 GO:0000779condensed chromosome, pericentric regionCC 0.008580.10185 GO:0000780condensed nuclear chromosome, pericentric regionCC 0.008580.10185 GO:0000502proteasome complex (sensu Eukaryota)CC 0.008520.1012 GO:0008170N-methyltransferase activityMF 0.002010.10076 GO:0006298mismatch repairBP 0.005590.1005 GO:0045005maintenance of fidelity during DNA-dependent DNA replicationBP 0.005590.1005 GO:0005740mitochondrial envelopeCC 0.019030.10048 GO:0006271DNA strand elongationBP 0.005550.09956 GO:0008080N-acetyltransferase activityMF 0.00390.09928 GO:0016407acetyltransferase activityMF 0.003920.09928 GO:0008276protein methyltransferase activityMF 0.001960.09903 GO:0003704specific RNA polymerase II transcription factor activityMF 0.003880.09869 GO:0009266response to temperature stimulusBP 0.00550.09866 GO:0009889regulation of biosynthesisBP 0.013950.09849 GO:0031326regulation of cellular biosynthesisBP 0.013950.09849 GO:0005657replication forkCC 0.008340.09795 GO:0030479actin cortical patchCC 0.008280.09795 GO:0006303double-strand break repair via nonhomologous end joiningBP 0.005460.0975 GO:0006030chitin metabolismBP 0.005440.0975 GO:0016044membrane organization and biogenesisBP 0.013880.09748 GO:0000737DNA catabolism, endonucleolyticBP 0.001970.09747 GO:0016879ligase activity, forming carbon-nitrogen bondsMF 0.003840.09707 GO:0006730one-carbon compound metabolismBP 0.013570.09572 GO:0001302replicative cell agingBP 0.013550.09556 GO:0006066alcohol metabolismBP 0.029120.09555 GO:0005887integral to plasma membraneCC 0.004280.09499 GO:0016887ATPase activityMF 0.008320.0944 GO:0001101response to acidBP 0.001890.09432 GO:0006289nucleotide-excision repairBP 0.013350.09391 GO:0043565sequence-specific DNA bindingMF 0.003730.09314 GO:0030001metal ion transportBP 0.013250.09306 GO:0030127COPII vesicle coatCC 0.002380.09298 GO:0012507ER to Golgi transport vesicle membraneCC 0.002380.09298 GO:0005663DNA replication factor C complexCC 0.002270.09242 GO:0000166nucleotide bindingMF 0.003690.09176 GO:0030658transport vesicle membraneCC 0.003990.09167 GO:0000124SAGA complexCC 0.0040.09167 GO:0030660Golgi-associated vesicle membraneCC 0.003990.09167 GO:0016279protein-lysine N-methyltransferase activityMF 0.001830.09144 GO:0016278lysine N-methyltransferase activityMF 0.001830.09144 GO:0000272polysaccharide catabolismBP 0.005130.09138 GO:0044247cellular polysaccharide catabolismBP 0.005130.09138 GO:0030952establishment and/or maintenance of cytoskeleton polarityBP 0.001820.09128 GO:0030950establishment and/or maintenance of actin cytoskeleton polarityBP 0.001820.09128 GO:0031490chromatin DNA bindingMF 0.000970.09101 GO:0000133polarisomeCC 0.002160.09063 GO:0051235maintenance of localizationBP 0.005080.09041 GO:0000152nuclear ubiquitin ligase complexCC 0.003850.09026 GO:0018193peptidyl-amino acid modificationBP 0.005070.0901 GO:0042138meiotic DNA double-strand break formationBP 0.001790.08975 GO:0008757S-adenosylmethionine-dependent methyltransferase activityMF 0.003630.0896 GO:0008213protein amino acid alkylationBP 0.005020.08935 GO:0006479protein amino acid methylationBP 0.005020.08935 GO:0051246regulation of protein metabolismBP 0.012730.08923 GO:0000142bud neck contractile ringCC 0.003770.08917 GO:0005826contractile ringCC 0.003770.08917 GO:0001558regulation of cell growthBP 0.0050.08896 GO:0000183chromatin silencing at rDNABP 0.004980.08871 GO:0006308DNA catabolismBP 0.004980.08828 GO:0019208phosphatase regulator activityMF 0.001760.08826 GO:0019888protein phosphatase regulator activityMF 0.001760.08826 GO:0009451RNA modificationBP 0.01260.08797 GO:0019318hexose metabolismBP 0.01250.08721 GO:0004596peptide alpha-N-acetyltransferase activityMF 0.000880.08718 GO:0005524ATP bindingMF 0.001730.08716 GO:0000151ubiquitin ligase complexCC 0.007390.08709 GO:0019210kinase inhibitor activityMF 0.000870.08655 GO:0031365N-terminal protein amino acid modificationBP 0.001720.08647 GO:0018409peptide or protein amino-terminal blockingBP 0.001720.08647 GO:0006474N-terminal protein amino acid acetylationBP 0.001720.08647 GO:0045010actin nucleationBP 0.001730.08647 GO:0043566structure-specific DNA bindingMF 0.003520.08584 GO:0000041transition metal ion transportBP 0.012310.08574 GO:0000707meiotic DNA recombinase assemblyBP 0.001710.08563 GO:0000730DNA recombinase assemblyBP 0.001710.08563 GO:0017038protein importBP 0.012270.08539 GO:0042623ATPase activity, coupledMF 0.007560.08406 GO:0031577spindle checkpointBP 0.004750.08405 GO:0007094mitotic spindle checkpointBP 0.004750.08405 GO:0000118histone deacetylase complexCC 0.003560.084 GO:0040008regulation of growthBP 0.004740.08396 GO:0042598vesicular fractionCC 0.003440.08324 GO:0005792microsomeCC 0.003440.08324 GO:0004519endonuclease activityMF 0.003410.08177 GO:0006301postreplication repairBP 0.004610.08177 GO:0007093mitotic checkpointBP 0.004590.08134 GO:0016579protein deubiquitinationBP 0.004590.08134 GO:0016491oxidoreductase activityMF 0.007330.08113 GO:0007021tubulin foldingBP 0.00160.08025 GO:0031570DNA integrity checkpointBP 0.004530.08015 GO:0003697single-stranded DNA bindingMF 0.001620.07924 GO:0000122negative regulation of transcription from RNA polymerase II promoterBP 0.011510.0791 GO:0000161MAPKKK cascade during osmolarity sensingBP 0.001570.07857 GO:0043085positive regulation of enzyme activityBP 0.001560.07802 GO:0030659cytoplasmic vesicle membraneCC 0.006530.07777 GO:0030662coated vesicle membraneCC 0.006530.07777 GO:0012506vesicle membraneCC 0.006530.07777 GO:0006445regulation of translationBP 0.01130.07739 GO:0000726non-recombinational repairBP 0.01130.07739 GO:0031966mitochondrial membraneCC 0.015320.07727 GO:0016071mRNA metabolismBP 0.024030.0768 GO:0000288mRNA catabolism, deadenylation-dependent decayBP 0.004330.07619 GO:0016125sterol metabolismBP 0.011120.076 GO:0005759mitochondrial matrixCC 0.015010.07551 GO:0031980mitochondrial lumenCC 0.015010.07551 GO:0030433ER-associated protein catabolismBP 0.011030.07522 GO:0005839proteasome core complex (sensu Eukaryota)CC 0.003020.07474 GO:0043596replication fork (sensu Eukaryota)CC 0.003010.07474 GO:0030894replisomeCC 0.003140.07474 GO:0043601replisome (sensu Eukaryota)CC 0.003140.07474 GO:0005838proteasome regulatory particle (sensu Eukaryota)CC 0.003110.07474 GO:0009101glycoprotein biosynthesisBP 0.010940.07464 GO:0016573histone acetylationBP 0.010940.07464 GO:0006400tRNA modificationBP 0.010910.07445 GO:0006073glucan metabolismBP 0.01090.07407 GO:0042763immature sporeCC 0.002970.07396 GO:0008023transcription elongation factor complexCC 0.002920.07396 GO:0005628prospore membraneCC 0.002970.07396 GO:0042764prosporeCC 0.002970.07396 GO:0005874microtubuleCC 0.00610.07365 GO:0019773proteasome core complex, alpha-subunit complex (sensu Eukaryota)CC 0.00170.07353 GO:0032161cleavage apparatus septin structureCC 0.001640.07353 GO:0000144bud neck septin ringCC 0.001640.07353 GO:0000399bud neck septin structureCC 0.001640.07353 GO:0006979response to oxidative stressBP 0.010810.07349 GO:0006800oxygen and reactive oxygen species metabolismBP 0.010820.07349 GO:0044433cytoplasmic vesicle partCC 0.005950.07196 GO:0005732small nucleolar ribonucleoprotein complexCC 0.005970.07196 GO:0051347positive regulation of transferase activityBP 0.001420.07178 GO:0045860positive regulation of protein kinase activityBP 0.001420.07178 GO:0042575DNA polymerase complexCC 0.001510.07169 GO:0006944membrane fusionBP 0.010530.07161 GO:0006006glucose metabolismBP 0.010540.07161 GO:0007050cell cycle arrestBP 0.004090.07136 GO:0019787small conjugating protein ligase activityMF 0.003120.07126 GO:0048475coated membraneCC 0.005880.07125 GO:0030117membrane coatCC 0.005880.07125 GO:0006417regulation of protein biosynthesisBP 0.010450.07086 GO:0031968organelle outer membraneCC 0.005830.07064 GO:0005741mitochondrial outer membraneCC 0.005830.07064 GO:0019867outer membraneCC 0.005830.07064 GO:0015674di-, tri-valent inorganic cation transportBP 0.010390.07062 GO:0005656pre-replicative complexCC 0.002720.0706 GO:0006631fatty acid metabolismBP 0.010270.06985 GO:0045786negative regulation of progression through cell cycleBP 0.004020.06974 GO:0006808regulation of nitrogen utilizationBP 0.001380.06966 GO:0051171regulation of nitrogen metabolismBP 0.001380.06966 GO:0006399tRNA metabolismBP 0.021910.06932 GO:0043413biopolymer glycosylationBP 0.010140.06886 GO:0006486protein amino acid glycosylationBP 0.010140.06886 GO:0009100glycoprotein metabolismBP 0.009970.06782 GO:0000196MAPKKK cascade during cell wall biogenesisBP 0.001350.06773 GO:0006405RNA export from nucleusBP 0.009890.0674 GO:0006515misfolded or incompletely synthesized protein catabolismBP 0.009860.0672 GO:0019866organelle inner membraneCC 0.013520.06711 GO:0006766vitamin metabolismBP 0.009850.06708 GO:0006767water-soluble vitamin metabolismBP 0.009850.06708 GO:0004860protein kinase inhibitor activityMF 0.000680.06676 GO:0051186cofactor metabolismBP 0.021040.06642 GO:0030120vesicle coatCC 0.005380.06639 GO:0043414biopolymer methylationBP 0.009710.06608 GO:0032259methylationBP 0.009710.06608 GO:0051082unfolded protein bindingMF 0.002930.06539 GO:0044275cellular carbohydrate catabolismBP 0.009520.065 GO:0016052carbohydrate catabolismBP 0.009520.065 GO:0045185maintenance of protein localizationBP 0.003810.06498 GO:0010035response to inorganic substanceBP 0.003810.06498 GO:0016881acid-amino acid ligase activityMF 0.002920.06481 GO:0008565protein transporter activityMF 0.002850.06281 GO:0016571histone methylationBP 0.003690.06274 GO:0005096GTPase activator activityMF 0.002840.06262 GO:0004536deoxyribonuclease activityMF 0.001310.06261 GO:00171085'-flap endonuclease activityMF 0.000590.06214 GO:0016888endodeoxyribonuclease activity, producing 5'-phosphomonoestersMF 0.000590.06214 GO:0048256flap endonuclease activityMF 0.000590.06214 GO:0051183vitamin transporter activityMF 0.000590.06214 GO:0030472mitotic spindle organization and biogenesis in nucleusBP 0.003660.06203 GO:0006811ion transportBP 0.019690.06188 GO:0000147actin cortical patch assemblyBP 0.003640.06171 GO:0006694steroid biosynthesisBP 0.009010.06152 GO:0016126sterol biosynthesisBP 0.009010.06152 GO:0030870Mre11 complexCC 0.001090.06147 GO:0005099Ras GTPase activator activityMF 0.001290.0614 GO:0046019regulation of transcription from RNA polymerase II promoter by pheromonesBP 0.001230.06123 GO:0009373regulation of transcription by pheromonesBP 0.001230.06123 GO:0006368RNA elongation from RNA polymerase II promoterBP 0.003610.0612 GO:0019740nitrogen utilizationBP 0.003610.0612 GO:0000375RNA splicing, via transesterification reactionsBP 0.019410.06089 GO:0005881cytoplasmic microtubuleCC 0.002130.06015 GO:0031301integral to organelle membraneCC 0.004770.05974 GO:0043094metabolic compound salvageBP 0.003550.05968 GO:0051273beta-glucan metabolismBP 0.001210.05959 GO:0016311dephosphorylationBP 0.008640.05906 GO:0042157lipoprotein metabolismBP 0.008610.05894 GO:0006497protein amino acid lipidationBP 0.008610.05894 GO:0042158lipoprotein biosynthesisBP 0.008610.05894 GO:0016072rRNA metabolismBP 0.018810.05891 GO:0010038response to metal ionBP 0.003490.05888 GO:0051274beta-glucan biosynthesisBP 0.001190.05886 GO:0000727double-strand break repair via break-induced replicationBP 0.001190.05836 GO:0018345protein palmitoylationBP 0.001180.05802 GO:0018318protein amino acid palmitoylationBP 0.001180.05802 GO:0006109regulation of carbohydrate metabolismBP 0.00340.05744 GO:0016874ligase activityMF 0.005820.0574 GO:0008234cysteine-type peptidase activityMF 0.001220.05735 GO:0007034vacuolar transportBP 0.018340.05727 GO:0015075ion transporter activityMF 0.005760.05722 GO:0031414N-terminal protein acetyltransferase complexCC 0.001010.0572 GO:0043625delta DNA polymerase complexCC 0.0010.0572 GO:0031248protein acetyltransferase complexCC 0.001010.0572 GO:0005884actin filamentCC 0.000950.0572 GO:0043241protein complex disassemblyBP 0.001170.05642 GO:0030473nuclear migration, microtubule-mediatedBP 0.003330.05635 GO:0007018microtubule-based movementBP 0.003330.05635 GO:0005743mitochondrial inner membraneCC 0.011840.05634 GO:0032182small conjugating protein bindingMF 0.000550.05629 GO:0015934large ribosomal subunitCC 0.011820.05611 GO:0006364rRNA processingBP 0.017910.05598 GO:0006606protein import into nucleusBP 0.008170.05597 GO:0051170nuclear importBP 0.008170.05597 GO:0000751cell cycle arrest in response to pheromoneBP 0.001150.05577 GO:0030674protein binding, bridgingMF 0.001190.05539 GO:0006272leading strand elongationBP 0.003270.05519 GO:00060751,3-beta-glucan biosynthesisBP 0.001130.05512 GO:00060741,3-beta-glucan metabolismBP 0.001130.05512 GO:0000903cellular morphogenesis during vegetative growthBP 0.001130.05512 GO:0031300intrinsic to organelle membraneCC 0.00430.05484 GO:0051647nucleus localizationBP 0.003240.05484 GO:0007097nuclear migrationBP 0.003240.05484 GO:0040023establishment of nucleus localizationBP 0.003240.05484 GO:0000321re-entry into mitotic cell cycle after pheromone arrestBP 0.001120.05466 GO:0000320re-entry into mitotic cell cycleBP 0.001120.05466 GO:0006091generation of precursor metabolites and energyBP 0.017410.05448 GO:0044452nucleolar partCC 0.011510.05399 GO:0004842ubiquitin-protein ligase activityMF 0.002590.05381 GO:0050658RNA transportBP 0.007820.05365 GO:0051236establishment of RNA localizationBP 0.007820.05365 GO:0050657nucleic acid transportBP 0.007820.05365 GO:0006997nuclear organization and biogenesisBP 0.007740.0531 GO:0006487protein amino acid N-linked glycosylationBP 0.007730.0531 GO:0030865cortical cytoskeleton organization and biogenesisBP 0.003160.05306 GO:0030866cortical actin cytoskeleton organization and biogenesisBP 0.003160.05306 GO:0006513protein monoubiquitinationBP 0.003110.05278 GO:0015631tubulin bindingMF 0.001140.05263 GO:0046519sphingoid metabolismBP 0.001090.05245 GO:0009117nucleotide metabolismBP 0.016720.05219 GO:0015980energy derivation by oxidation of organic compoundsBP 0.016680.05212 GO:0009250glucan biosynthesisBP 0.003050.05203 GO:0003702RNA polymerase II transcription factor activityMF 0.004870.05175 GO:0016564transcriptional repressor activityMF 0.002540.05159 GO:0006406mRNA export from nucleusBP 0.007450.05125 GO:0051028mRNA transportBP 0.007450.05125 GO:0006732coenzyme metabolismBP 0.01630.05053 GO:0008204ergosterol metabolismBP 0.002920.05002 GO:0006696ergosterol biosynthesisBP 0.002920.05002 GO:0006334nucleosome assemblyBP 0.002920.04975 GO:0000742karyogamy during conjugation with cellular fusionBP 0.002880.04938 GO:0000741karyogamyBP 0.002880.04938 GO:0030003cation homeostasisBP 0.007090.04886 GO:0008233peptidase activityMF 0.004540.04879 GO:0030482actin cableCC 0.000670.04876 GO:0031415NatA complexCC 0.000780.04876 GO:0005869dynactin complexCC 0.00070.04876 GO:0031422RecQ helicase-Topo III complexCC 0.000790.04876 GO:0032432actin filament bundleCC 0.000670.04876 GO:0016272prefoldin complexCC 0.000660.04876 GO:0000808origin recognition complexCC 0.000910.04876 GO:0005664nuclear origin of replication recognition complexCC 0.000910.04876 GO:0005678chromatin assembly complexCC 0.000830.04876 GO:0010033response to organic substanceBP 0.001030.04873 GO:0016575histone deacetylationBP 0.002830.04864 GO:0004386helicase activityMF 0.002460.04826 GO:0006476protein amino acid deacetylationBP 0.00280.04821 GO:0003714transcription corepressor activityMF 0.001060.04737 GO:0005868cytoplasmic dynein complexCC 0.00060.04736 GO:0030286dynein complexCC 0.00060.04736 GO:0045121lipid raftCC 0.000640.04736 GO:0030140trans-Golgi network transport vesicleCC 0.000630.04736 GO:0006470protein amino acid dephosphorylationBP 0.002750.04734 GO:0000209protein polyubiquitinationBP 0.002730.04697 GO:0042144vacuole fusion, non-autophagicBP 0.00270.04657 GO:0046695SLIK (SAGA-like) complexCC 0.001340.04617 GO:0048284organelle fusionBP 0.002670.04617 GO:0048188COMPASS complexCC 0.000550.04592 GO:0035097histone methyltransferase complexCC 0.000550.04592 GO:0008623chromatin accessibility complexCC 0.000550.04592 GO:0006519amino acid and derivative metabolismBP 0.015010.04563 GO:0006733oxidoreduction coenzyme metabolismBP 0.006630.04544 GO:0015931nucleobase, nucleoside, nucleotide and nucleic acid transportBP 0.006610.04531 GO:0004857enzyme inhibitor activityMF 0.001030.04513 GO:0008610lipid biosynthesisBP 0.014810.0449 GO:0015837amine transportBP 0.006570.04478 GO:0042578phosphoric ester hydrolase activityMF 0.004120.04469 GO:0005871kinesin complexCC 0.000490.04467 GO:0005885Arp2/3 protein complexCC 0.000470.04467 GO:0006906vesicle fusionBP 0.002560.04463 GO:0000377RNA splicing, via transesterification reactions with bulged adenosine as nucleophileBP 0.006490.04424 GO:0000083G1/S-specific transcription in mitotic cell cycleBP 0.002520.04422 GO:0000109nucleotide-excision repair complexCC 0.001210.04402 GO:0051184cofactor transporter activityMF 0.001010.04367 GO:0006397mRNA processingBP 0.014460.04358 GO:0016944RNA polymerase II transcription elongation factor activityMF 0.001010.04334 GO:0008033tRNA processingBP 0.006290.04225 GO:0000722telomere maintenance via recombinationBP 0.002380.04208 GO:0051223regulation of protein transportBP 0.000910.04127 GO:0004520endodeoxyribonuclease activityMF 0.000980.04112 GO:0030490processing of 20S pre-rRNABP 0.006170.0411 GO:0009414response to water deprivationBP 0.00090.04097 GO:0009415response to waterBP 0.00090.04097 GO:0009269response to desiccationBP 0.00090.04097 GO:0004529exodeoxyribonuclease activityMF 0.000420.04078 GO:0008324cation transporter activityMF 0.003720.04062 GO:0008541proteasome regulatory particle, lid subcomplex (sensu Eukaryota)CC 0.000430.04058 GO:0008540proteasome regulatory particle, base subcomplex (sensu Eukaryota)CC 0.000420.04058 GO:0015846polyamine transportBP 0.000890.04054 GO:0006354RNA elongationBP 0.006110.04046 GO:0003711transcriptional elongation regulator activityMF 0.000970.04035 GO:0006112energy reserve metabolismBP 0.006080.04018 GO:0019707protein-cysteine S-acyltransferase activityMF 0.00040.04012 GO:0019706protein-cysteine S-palmitoleyltransferase activityMF 0.00040.04012 GO:0016485protein processingBP 0.006060.04002 GO:0005216ion channel activityMF 0.00040.03996 GO:0008297single-stranded DNA specific exodeoxyribonuclease activityMF 0.000390.03954 GO:0008310single-stranded DNA specific 3'-5' exodeoxyribonuclease activityMF 0.000390.03954 GO:0003891delta DNA polymerase activityMF 0.000390.03954 GO:0005199structural constituent of cell wallMF 0.000960.03905 GO:00084083'-5' exonuclease activityMF 0.000950.03877 GO:0006665sphingolipid metabolismBP 0.002170.03861 GO:0016459myosin complexCC 0.000370.03849 GO:0043173nucleotide salvageBP 0.000840.0381 GO:0048278vesicle dockingBP 0.002110.03804 GO:0016779nucleotidyltransferase activityMF 0.002230.03787 GO:0003700transcription factor activityMF 0.002220.03767 GO:0016796exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoestersMF 0.000940.03751 GO:0006280mutagenesisBP 0.000810.03719 GO:0051180vitamin transportBP 0.000810.03719 GO:0005576extracellular regionCC 0.0010.03702 GO:0046983protein dimerization activityMF 0.000370.03698 GO:00082963'-5'-exodeoxyribonuclease activityMF 0.000370.03698 GO:0016895exodeoxyribonuclease activity, producing 5'-phosphomonoestersMF 0.000370.03698 GO:0019898extrinsic to membraneCC 0.003260.03665 GO:0003690double-stranded DNA bindingMF 0.000930.03661 GO:0051439regulation of ubiquitin ligase activity during mitotic cell cycleBP 0.000770.03577 GO:0051340regulation of ligase activityBP 0.000770.03577 GO:0051438regulation of ubiquitin ligase activityBP 0.000770.03577 GO:0006611protein export from nucleusBP 0.005630.03571 GO:0000110nucleotide-excision repair factor 1 complexCC 0.000270.03539 GO:0006869lipid transportBP 0.005580.03524 GO:0000090mitotic anaphaseBP 0.000760.03507 GO:0051322anaphaseBP 0.000760.03507 GO:0006450regulation of translational fidelityBP 0.001930.03506 GO:0006520amino acid metabolismBP 0.011760.03502 GO:0006401RNA catabolismBP 0.005540.03467 GO:0046915transition metal ion transporter activityMF 0.00090.0346 GO:0009607response to biotic stimulusBP 0.001910.0346 GO:0019362pyridine nucleotide metabolismBP 0.005510.03442 GO:0006336DNA replication-independent nucleosome assemblyBP 0.000740.03431 GO:0007346regulation of progression through mitotic cell cycleBP 0.00190.03428 GO:0016574histone ubiquitinationBP 0.000730.03417 GO:0051436negative regulation of ubiquitin ligase activity during mitotic cell cycleBP 0.000710.03329 GO:0051352negative regulation of ligase activityBP 0.000710.03329 GO:0051444negative regulation of ubiquitin ligase activityBP 0.000710.03329 GO:0008639small protein conjugating enzyme activityMF 0.000880.03309 GO:0030136clathrin-coated vesicleCC 0.002980.03286 GO:0005768endosomeCC 0.002960.03262 GO:0009749response to glucose stimulusBP 0.00070.03258 GO:0009746response to hexose stimulusBP 0.00070.03258 GO:0006904vesicle docking during exocytosisBP 0.00180.03229 GO:0016417S-acyltransferase activityMF 0.000870.03218 GO:0008134transcription factor bindingMF 0.002070.03217 GO:0008202steroid metabolismBP 0.00530.03193 GO:0001301progressive alteration of chromatin during cell agingBP 0.000660.03128 GO:0000117G2/M-specific transcription in mitotic cell cycleBP 0.000660.03109 GO:0005761mitochondrial ribosomeCC 0.002850.0308 GO:0000313organellar ribosomeCC 0.002850.0308 GO:0006885regulation of pHBP 0.001710.0305 GO:0000784nuclear chromosome, telomeric regionCC 0.000810.03047 GO:0031123RNA 3'-end processingBP 0.00170.03035 GO:0008375acetylglucosaminyltransferase activityMF 0.000330.03009 GO:0005088Ras guanyl-nucleotide exchange factor activityMF 0.000350.03009 GO:0043086negative regulation of enzyme activityBP 0.000630.03004 GO:0051789response to protein stimulusBP 0.001690.03002 GO:0006986response to unfolded proteinBP 0.001690.03002 GO:0042493response to drugBP 0.005120.02981 GO:0045333cellular respirationBP 0.005120.02981 GO:0051252regulation of RNA metabolismBP 0.001680.02976 GO:0009110vitamin biosynthesisBP 0.005110.02973 GO:0042364water-soluble vitamin biosynthesisBP 0.005110.02973 GO:0006284base-excision repairBP 0.001670.02955 GO:0043254regulation of protein complex assemblyBP 0.000610.02946 GO:0003712transcription cofactor activityMF 0.001950.02928 GO:0031228intrinsic to Golgi membraneCC 0.000770.02925 GO:0030173integral to Golgi membraneCC 0.000770.02925 GO:0007157heterophilic cell adhesionBP 0.001640.02838 GO:0044455mitochondrial membrane partCC 0.002690.02821 GO:0000781chromosome, telomeric regionCC 0.000750.02813 GO:0005876spindle microtubuleCC 0.000740.02794 GO:0003678DNA helicase activityMF 0.001880.02792 GO:0007029endoplasmic reticulum organization and biogenesisBP 0.000580.02725 GO:0030100regulation of endocytosisBP 0.000570.02708 GO:0031124mRNA 3'-end processingBP 0.001610.02707 GO:0044453nuclear membrane partCC 0.002660.02706 GO:0031965nuclear membraneCC 0.002660.02706 GO:0044271nitrogen compound biosynthesisBP 0.007070.02637 GO:0009309amine biosynthesisBP 0.007070.02637 GO:0008652amino acid biosynthesisBP 0.006280.02637 GO:0008157protein phosphatase 1 bindingMF 0.000310.02624 GO:0019903protein phosphatase bindingMF 0.000310.02624 GO:0019902phosphatase bindingMF 0.000310.02624 GO:0004540ribonuclease activityMF 0.001760.02519 GO:0044462external encapsulating structure partCC 0.000160.02464 GO:0044426cell wall partCC 0.000160.02464 GO:0031932TORC 2 complexCC 0.000160.02464 GO:0048017inositol lipid-mediated signalingBP 0.001550.02442 GO:0048015phosphoinositide-mediated signalingBP 0.001550.02442 GO:0008599protein phosphatase type 1 regulator activityMF 0.000790.02412 GO:0009306protein secretionBP 0.000510.02406 GO:0015758glucose transportBP 0.00050.02406 GO:0016811hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidesMF 0.001680.0239 GO:0008194UDP-glycosyltransferase activityMF 0.000770.02345 GO:0046467membrane lipid biosynthesisBP 0.004570.02335 GO:0016903oxidoreductase activity, acting on the aldehyde or oxo group of donorsMF 0.000770.02328 GO:0000398nuclear mRNA splicing, via spliceosomeBP 0.004560.02321 GO:0016237microautophagyBP 0.000490.02252 GO:0006369transcription termination from RNA polymerase II promoterBP 0.00150.02226 GO:0016337cell-cell adhesionBP 0.001510.02226 GO:0006265DNA topological changeBP 0.000490.02211 GO:0004428inositol or phosphatidylinositol kinase activityMF 0.000740.02168 GO:0005386carrier activityMF 0.001590.02165 GO:0003729mRNA bindingMF 0.001580.02165 GO:0009060aerobic respirationBP 0.004390.02151 GO:0005275amine transporter activityMF 0.001560.02131 GO:0005319lipid transporter activityMF 0.000730.02126 GO:0042724thiamin and derivative biosynthesisBP 0.001470.02125 GO:0007155cell adhesionBP 0.001470.02125 GO:0006092main pathways of carbohydrate metabolismBP 0.004360.02119 GO:0005643nuclear poreCC 0.002380.02104 GO:0046930pore complexCC 0.002380.02104 GO:0000002mitochondrial genome maintenanceBP 0.004330.02089 GO:0005778peroxisomal membraneCC 0.000650.02088 GO:0000782telomere cap complexCC 0.000650.02088 GO:0000783nuclear telomere cap complexCC 0.000650.02088 GO:0031903microbody membraneCC 0.000650.02088 GO:0045182translation regulator activityMF 0.001520.02033 GO:0009228thiamin biosynthesisBP 0.001440.02031 GO:0000014single-stranded DNA specific endodeoxyribonuclease activityMF 0.000280.02011 GO:0015082di-, tri-valent inorganic cation transporter activityMF 0.001490.01988 GO:0016627oxidoreductase activity, acting on the CH-CH group of donorsMF 0.000710.0197 GO:0016298lipase activityMF 0.000710.0197 GO:0042723thiamin and derivative metabolismBP 0.001420.01969 GO:0006094gluconeogenesisBP 0.001420.01969 GO:0000033alpha-1,3-mannosyltransferase activityMF 0.000280.0195 GO:0043492ATPase activity, coupled to movement of substancesMF 0.001470.01944 GO:0042626ATPase activity, coupled to transmembrane movement of substancesMF 0.001470.01944 GO:0016820hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substancesMF 0.001470.01944 GO:0006560proline metabolismBP 0.000450.01934 GO:0005478intracellular transporter activityMF 0.000690.01886 GO:0016810hydrolase activity, acting on carbon-nitrogen (but not peptide) bondsMF 0.001440.01885 GO:0030148sphingolipid biosynthesisBP 0.00140.01883 GO:0001300chronological cell agingBP 0.001410.01883 GO:0051318G1 phaseBP 0.00140.01883 GO:0000080G1 phase of mitotic cell cycleBP 0.00140.01883 GO:0004175endopeptidase activityMF 0.001430.0186 GO:0046873metal ion transporter activityMF 0.001420.01833 GO:0004527exonuclease activityMF 0.00140.01821 GO:0007004telomere maintenance via telomeraseBP 0.001380.01819 GO:0045815positive regulation of gene expression, epigeneticBP 0.000420.01789 GO:0006345loss of chromatin silencingBP 0.000420.01789 GO:0005681spliceosome complexCC 0.00220.01785 GO:0046364monosaccharide biosynthesisBP 0.001370.01781 GO:0019319hexose biosynthesisBP 0.001370.01781 GO:0016409palmitoyltransferase activityMF 0.000660.0178 GO:0045835negative regulation of meiosisBP 0.000410.0177 GO:0008094DNA-dependent ATPase activityMF 0.001370.01757 GO:0006276plasmid maintenanceBP 0.000410.01754 GO:0005779integral to peroxisomal membraneCC 0.00010.01742 GO:0000408EKC/KEOPS protein complexCC 0.00010.01742 GO:0043291RAVE complexCC 0.00010.01742 GO:0031231intrinsic to peroxisomal membraneCC 0.00010.01742 GO:0008654phospholipid biosynthesisBP 0.003930.01733 GO:0009408response to heatBP 0.001350.01724 GO:0006875metal ion homeostasisBP 0.003910.01717 GO:0006612protein targeting to membraneBP 0.003890.017 GO:0030005di-, tri-valent inorganic cation homeostasisBP 0.003880.017 GO:0016197endosome transportBP 0.003880.01695 GO:0006388tRNA splicingBP 0.001330.01685 GO:0006879iron ion homeostasisBP 0.001330.01685 GO:0000394RNA splicing, via endonucleolytic cleavage and ligationBP 0.001330.01685 GO:0006493protein amino acid O-linked glycosylationBP 0.001330.01685 GO:0005763mitochondrial small ribosomal subunitCC 0.002130.01675 GO:0000314organellar small ribosomal subunitCC 0.002130.01675 GO:0007129synapsisBP 0.00040.01671 GO:0016789carboxylic ester hydrolase activityMF 0.001280.0166 GO:0015293symporter activityMF 0.000260.01656 GO:0000812SWR1 complexCC 0.000610.01649 GO:0006402mRNA catabolismBP 0.00380.01638 GO:0016763transferase activity, transferring pentosyl groupsMF 0.000620.01633 GO:0046165alcohol biosynthesisBP 0.003790.01632 GO:0006268DNA unwinding during replicationBP 0.001320.0163 GO:0032392DNA geometric changeBP 0.001320.0163 GO:0004521endoribonuclease activityMF 0.000620.01629 GO:0044439peroxisomal partCC 0.002090.01621 GO:0044438microbody partCC 0.002090.01621 GO:0019899enzyme bindingMF 0.000620.01606 GO:0045851pH reductionBP 0.001310.01601 GO:0051452cellular pH reductionBP 0.001310.01601 GO:0007035vacuolar acidificationBP 0.001310.01601 GO:0006865amino acid transportBP 0.003740.01598 GO:0000290deadenylation-dependent decappingBP 0.000390.01592 GO:0030004monovalent inorganic cation homeostasisBP 0.003730.01585 GO:0006772thiamin metabolismBP 0.00130.0158 GO:0006353transcription terminationBP 0.001290.01564 GO:0008173RNA methyltransferase activityMF 0.000610.0156 GO:0046483heterocycle metabolismBP 0.003690.01559 GO:000636535S primary transcript processingBP 0.003690.01559 GO:0006378mRNA polyadenylationBP 0.001290.01556 GO:0006725aromatic compound metabolismBP 0.003670.01549 GO:0031984organelle subcompartmentCC 0.000590.01525 GO:0031985Golgi cisternaCC 0.000590.01525 GO:0005795Golgi stackCC 0.000590.01525 GO:0006352transcription initiationBP 0.003620.01508 GO:0015926glucosidase activityMF 0.000580.01475 GO:0009894regulation of catabolismBP 0.001260.01473 GO:0008643carbohydrate transportBP 0.003540.01456 GO:0043631RNA polyadenylationBP 0.001260.01456 GO:0019897extrinsic to plasma membraneCC 0.000560.01443 GO:0005770late endosomeCC 0.000560.01443 GO:0046942carboxylic acid transportBP 0.003510.01437 GO:0015294solute:cation symporter activityMF 0.000250.01409 GO:0009890negative regulation of biosynthesisBP 0.000380.01408 GO:0016478negative regulation of translationBP 0.000380.01408 GO:0031327negative regulation of cellular biosynthesisBP 0.000380.01408 GO:0017148negative regulation of protein biosynthesisBP 0.000380.01408 GO:0030846transcription termination from Pol II promoter, RNA polymerase(A) coupledBP 0.000380.01408 GO:0016251general RNA polymerase II transcription factor activityMF 0.001110.01407 GO:0046474glycerophospholipid biosynthesisBP 0.003460.01406 GO:0016893endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoestersMF 0.000570.01399 GO:0005802Golgi trans faceCC 0.000550.01397 GO:0009260ribonucleotide biosynthesisBP 0.003430.01379 GO:0006790sulfur metabolismBP 0.003430.01379 GO:0015239multidrug transporter activityMF 0.000560.01378 GO:0030532small nuclear ribonucleoprotein complexCC 0.001910.01375 GO:0016614oxidoreductase activity, acting on CH-OH group of donorsMF 0.001080.01366 GO:0006163purine nucleotide metabolismBP 0.003380.01352 GO:0006825copper ion transportBP 0.001230.01349 GO:0043574peroxisomal transportBP 0.001230.01349 GO:0006625protein targeting to peroxisomeBP 0.001230.01349 GO:0009259ribonucleotide metabolismBP 0.003370.01348 GO:0006113fermentationBP 0.001220.01338 GO:0000731DNA synthesis during DNA repairBP 0.000370.01337 GO:0008301DNA bending activityMF 0.000550.01322 GO:0006414translational elongationBP 0.001210.01322 GO:0030641hydrogen ion homeostasisBP 0.001210.01322 GO:0051453regulation of cellular pHBP 0.001210.01322 GO:0008026ATP-dependent helicase activityMF 0.001050.0132 GO:0045996negative regulation of transcription by pheromonesBP 0.000360.01319 GO:0046020negative regulation of transcription from RNA polymerase II promoter by pheromonesBP 0.000360.01319 GO:0009743response to carbohydrate stimulusBP 0.000360.01317 GO:0015849organic acid transportBP 0.003310.01317 GO:0016620oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptorMF 0.000550.01307 GO:0005342organic acid transporter activityMF 0.001050.01306 GO:0046916transition metal ion homeostasisBP 0.003290.01303 GO:0006090pyruvate metabolismBP 0.003280.01297 GO:0004402histone acetyltransferase activityMF 0.000540.01294 GO:0004468lysine N-acetyltransferase activityMF 0.000540.01294 GO:0004553hydrolase activity, hydrolyzing O-glycosyl compoundsMF 0.001030.01286 GO:0046982protein heterodimerization activityMF 0.000240.01282 GO:0000054ribosome export from nucleusBP 0.00120.01268 GO:0008287protein serine/threonine phosphatase complexCC 0.000530.01265 GO:0005978glycogen biosynthesisBP 0.001190.0125 GO:0005684major (U2-dependent) spliceosomeCC 0.001690.01247 GO:0000710meiotic mismatch repairBP 0.000350.01243 GO:0006650glycerophospholipid metabolismBP 0.003180.01242 GO:0030384phosphoinositide metabolismBP 0.003150.01229 GO:0016791phosphoric monoester hydrolase activityMF 0.000980.01206 GO:0043488regulation of mRNA stabilityBP 0.001170.012 GO:0043487regulation of RNA stabilityBP 0.001170.012 GO:0015672monovalent inorganic cation transportBP 0.001170.012 GO:0009165nucleotide biosynthesisBP 0.003070.01197 GO:0006119oxidative phosphorylationBP 0.003060.01193 GO:0019932second-messenger-mediated signalingBP 0.003060.01193 GO:0042255ribosome assemblyBP 0.003060.01191 GO:0016591DNA-directed RNA polymerase II, holoenzymeCC 0.001530.01191 GO:0042579microbodyCC 0.001540.01191 GO:0005777peroxisomeCC 0.001540.01191 GO:0016853isomerase activityMF 0.000960.01183 GO:0043255regulation of carbohydrate biosynthesisBP 0.001160.01179 GO:0015918sterol transportBP 0.001160.01179 GO:0046470phosphatidylcholine metabolismBP 0.000330.01172 GO:0006413translational initiationBP 0.003010.01171 GO:0001510RNA methylationBP 0.001160.01161 GO:0006839mitochondrial transportBP 0.002970.01157 GO:0042257ribosomal subunit assemblyBP 0.002960.01155 GO:0006998nuclear membrane organization and biogenesisBP 0.000330.01155 GO:0005680anaphase-promoting complexCC 0.000510.01155 GO:0000300peripheral to membrane of membrane fractionCC 0.000510.01155 GO:0030176integral to endoplasmic reticulum membraneCC 0.000510.01155 GO:0031227intrinsic to endoplasmic reticulum membraneCC 0.000510.01155 GO:0042800histone lysine N-methyltransferase activity (H3-K4 specific)MF 0.000220.0115 GO:0031202RNA splicing factor activity, transesterification mechanismMF 0.000940.0115 GO:0043681protein import into mitochondrionBP 0.002950.01149 GO:0016616oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorMF 0.000930.01138 GO:0006164purine nucleotide biosynthesisBP 0.002910.01137 GO:0015680intracellular copper ion transportBP 0.000330.01137 GO:0006367transcription initiation from RNA polymerase II promoterBP 0.002910.01137 GO:0009150purine ribonucleotide metabolismBP 0.002860.01117 GO:0044270nitrogen compound catabolismBP 0.002850.01115 GO:0009310amine catabolismBP 0.002850.01115 GO:0042147retrograde transport, endosome to GolgiBP 0.001140.01106 GO:0006626protein targeting to mitochondrionBP 0.00280.01101 GO:0009152purine ribonucleotide biosynthesisBP 0.002770.01091 GO:0000315organellar large ribosomal subunitCC 0.001350.01087 GO:0005762mitochondrial large ribosomal subunitCC 0.001350.01087 GO:0007265Ras protein signal transductionBP 0.001130.01083 GO:0004003ATP-dependent DNA helicase activityMF 0.000480.01083 GO:0046943carboxylic acid transporter activityMF 0.000880.01083 GO:0015171amino acid transporter activityMF 0.000880.01078 GO:0009108coenzyme biosynthesisBP 0.002720.01077 GO:0015077monovalent inorganic cation transporter activityMF 0.000870.01067 GO:0000077DNA damage checkpointBP 0.001130.01062 GO:0042770DNA damage response, signal transductionBP 0.001130.01062 GO:0030515snoRNA bindingMF 0.000470.01057 GO:0000027ribosomal large subunit assembly and maintenanceBP 0.002630.01056 GO:0051231spindle elongationBP 0.001120.01055 GO:0000022mitotic spindle elongationBP 0.001120.01055 GO:0004523ribonuclease H activityMF 0.000210.01054 GO:0042277peptide bindingMF 0.000470.01053 GO:0005048signal sequence bindingMF 0.000470.01053 GO:0051188cofactor biosynthesisBP 0.00260.01052 GO:0031312extrinsic to organelle membraneCC 0.000490.01051 GO:0009064glutamine family amino acid metabolismBP 0.002590.01049 GO:0030491heteroduplex formationBP 0.000320.01046 GO:0015238drug transporter activityMF 0.000470.01045 GO:0008054cyclin catabolismBP 0.001120.01044 GO:0016798hydrolase activity, acting on glycosyl bondsMF 0.000840.01042 GO:0009112nucleobase metabolismBP 0.002530.01039 GO:0004721phosphoprotein phosphatase activityMF 0.000840.01037 GO:0005844polysomeCC 0.000490.01037 GO:0045047protein targeting to ERBP 0.00250.01035 GO:0005782peroxisomal matrixCC 0.000490.01034 GO:0006383transcription from RNA polymerase III promoterBP 0.002450.01026 GO:0006752group transfer coenzyme metabolismBP 0.002430.01024 GO:0008135translation factor activity, nucleic acid bindingMF 0.000820.01022 GO:0006769nicotinamide metabolismBP 0.002410.0102 GO:0015078hydrogen ion transporter activityMF 0.000810.01014 GO:0006874calcium ion homeostasisBP 0.000320.01013 GO:0016925protein sumoylationBP 0.000320.01013 GO:0019320hexose catabolismBP 0.002250.01004 GO:0046164alcohol catabolismBP 0.002240.01004 GO:0006007glucose catabolismBP 0.002070.00988 GO:0046365monosaccharide catabolismBP 0.002060.00987 GO:0007130synaptonemal complex formationBP 0.000310.00983 GO:0005811lipid particleCC 0.001090.00972 GO:0009066aspartate family amino acid metabolismBP 0.001790.0097 GO:0008175tRNA methyltransferase activityMF 0.000450.00969 GO:0005381iron ion transporter activityMF 0.000450.00969 GO:0003743translation initiation factor activityMF 0.000440.00969 GO:0003724RNA helicase activityMF 0.000740.00967 GO:0030014CCR4-NOT complexCC 0.000470.00956 GO:0016829lyase activityMF 0.000710.00954 GO:0042594response to starvationBP 0.001090.00952 GO:0031668cellular response to extracellular stimulusBP 0.001090.00952 GO:0031669cellular response to nutrient levelsBP 0.001090.00952 GO:0009267cellular response to starvationBP 0.001090.00952 GO:0016050vesicle organization and biogenesisBP 0.001090.00952 GO:0051716cellular response to stimulusBP 0.001090.00952 GO:0005484SNAP receptor activityMF 0.000440.00942 GO:0005847mRNA cleavage and polyadenylation specificity factor complexCC 0.000470.00939 GO:0030541plasmid partitioningBP 0.000310.00936 GO:00305432-micrometer plasmid partitioningBP 0.000310.00936 GO:0051336regulation of hydrolase activityBP 0.000310.00936 GO:0043666regulation of phosphoprotein phosphatase activityBP 0.000310.00936 GO:0009063amino acid catabolismBP 0.001080.00935 GO:0008645hexose transportBP 0.001080.00932 GO:0015749monosaccharide transportBP 0.001080.00932 GO:0051248negative regulation of protein metabolismBP 0.001080.00924 GO:0007023post-chaperonin tubulin folding pathwayBP 0.000310.00917 GO:0045721negative regulation of gluconeogenesisBP 0.00030.00916 GO:0045912negative regulation of carbohydrate metabolismBP 0.00030.00916 GO:0016836hydro-lyase activityMF 0.000430.00909 GO:0015290electrochemical potential-driven transporter activityMF 0.000570.00905 GO:0015291porter activityMF 0.000570.00905 GO:0016835carbon-oxygen lyase activityMF 0.000550.00895 GO:0045002double-strand break repair via single-strand annealingBP 0.001070.00895 GO:0030880RNA polymerase complexCC 0.000790.00888 GO:0006118electron transportBP 0.001320.00887 GO:0000096sulfur amino acid metabolismBP 0.001670.00887 GO:0043101purine salvageBP 0.00030.00886 GO:0015992proton transportBP 0.001070.00883 GO:0006818hydrogen transportBP 0.001070.00883 GO:0031970organelle envelope lumenCC 0.000460.00878 GO:0005758mitochondrial intermembrane spaceCC 0.000460.00878 GO:0000056ribosomal small subunit export from nucleusBP 0.00030.00876 GO:0016765transferase activity, transferring alkyl or aryl (other than methyl) groupsMF 0.000380.00865 GO:0016586RSC complexCC 0.000450.00864 GO:0000164protein phosphatase type 1 complexCC 8e-050.00855 GO:0006890retrograde vesicle-mediated transport, Golgi to ERBP 0.001050.0085 GO:0019789SUMO ligase activityMF 0.000190.00849 GO:0003899DNA-directed RNA polymerase activityMF 0.000330.00849 GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolismBP 0.001050.00835 GO:0007091mitotic metaphase/anaphase transitionBP 0.001050.00835 GO:0006111regulation of gluconeogenesisBP 0.001040.00818 GO:0016876ligase activity, forming aminoacyl-tRNA and related compoundsMF 0.000140.00814 GO:0004812aminoacyl-tRNA ligase activityMF 0.000140.00814 GO:0016875ligase activity, forming carbon-oxygen bondsMF 0.000140.00814 GO:0001727lipid kinase activityMF 0.000190.00806 GO:0015144carbohydrate transporter activityMF 0.000390.00806 GO:0051247positive regulation of protein metabolismBP 0.000290.00789 GO:0046394carboxylic acid biosynthesisBP 0.001020.00786 GO:0016053organic acid biosynthesisBP 0.001020.00786 GO:0005637nuclear inner membraneCC 8e-050.00786 GO:0003713transcription coactivator activityMF 0.000380.00776 GO:0008535cytochrome c oxidase complex assemblyBP 0.000280.00749 GO:0016233telomere cappingBP 0.000280.00734 GO:0043144snoRNA processingBP 0.000280.00734 GO:0000771agglutinationBP 0.000280.0073 GO:0000752agglutination during conjugation with cellular fusionBP 0.000280.0073 GO:0030488tRNA methylationBP 0.000990.00727 GO:0043189H4/H2A histone acetyltransferase complexCC 0.000430.00724 GO:0006576biogenic amine metabolismBP 0.000990.00722 GO:0000245spliceosome assemblyBP 0.000980.0072 GO:0007039vacuolar protein catabolismBP 0.000980.00717 GO:0051181cofactor transportBP 0.000280.00706 GO:0016074snoRNA metabolismBP 0.000970.00699 GO:0005529sugar bindingMF 0.000180.00697 GO:0004406H3/H4 histone acetyltransferase activityMF 0.000180.00697 GO:0017136NAD-dependent histone deacetylase activityMF 0.000180.00697 GO:0016597amino acid bindingMF 0.000180.00697 GO:0043176amine bindingMF 0.000180.00697 GO:0019213deacetylase activityMF 0.000350.00694 GO:0006144purine base metabolismBP 0.000960.00692 GO:0006613cotranslational protein targeting to membraneBP 0.000960.00691 GO:0006575amino acid derivative metabolismBP 0.000960.00683 GO:0006749glutathione metabolismBP 0.000270.00681 GO:0003688DNA replication origin bindingMF 0.000340.00673 GO:0030246carbohydrate bindingMF 0.000170.00673 GO:0000028ribosomal small subunit assembly and maintenanceBP 0.000950.00672 GO:0006633fatty acid biosynthesisBP 0.000950.00672 GO:0005979regulation of glycogen biosynthesisBP 0.000270.00669 GO:0006896Golgi to vacuole transportBP 0.000930.00641 GO:0003680AT DNA bindingMF 0.000170.00636 GO:0004806triacylglycerol lipase activityMF 0.000170.00636 GO:0005977glycogen metabolismBP 0.000920.00634 GO:0006360transcription from RNA polymerase I promoterBP 0.000920.00628 GO:0016896exoribonuclease activity, producing 5'-phosphomonoestersMF 0.000320.00623 GO:0004532exoribonuclease activityMF 0.000320.00623 GO:0042625ATPase activity, coupled to transmembrane movement of ionsMF 0.000310.00623 GO:0008186RNA-dependent ATPase activityMF 0.000320.00623 GO:0005753proton-transporting ATP synthase complex (sensu Eukaryota)CC 0.00040.00615 GO:0016469proton-transporting two-sector ATPase complexCC 0.00040.00615 GO:0045255hydrogen-translocating F-type ATPase complexCC 0.00040.00615 GO:0045259proton-transporting ATP synthase complexCC 0.00040.00615 GO:0048029monosaccharide bindingMF 0.000160.0061 GO:0003964RNA-directed DNA polymerase activityMF 0.000170.0061 GO:0015268alpha-type channel activityMF 0.00030.00605 GO:0015267channel or pore class transporter activityMF 0.00030.00605 GO:0042054histone methyltransferase activityMF 0.000160.00603 GO:0000032cell wall mannoprotein biosynthesisBP 0.00090.00603 GO:0018024histone-lysine N-methyltransferase activityMF 0.000160.00603 GO:0006056mannoprotein metabolismBP 0.00090.00603 GO:0031506cell wall glycoprotein biosynthesisBP 0.00090.00603 GO:0006057mannoprotein biosynthesisBP 0.00090.00603 GO:0008028monocarboxylic acid transporter activityMF 0.00030.00599 GO:0044450microtubule organizing center partCC 0.000390.00594 GO:0016651oxidoreductase activity, acting on NADH or NADPHMF 0.000290.0059 GO:0009055electron carrier activityMF 0.000290.0059 GO:0004407histone deacetylase activityMF 0.000290.0059 GO:0032045guanyl-nucleotide exchange factor complexCC 8e-050.00587 GO:0000795synaptonemal complexCC 8e-050.00587 GO:0000506glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complexCC 8e-050.00587 GO:0005619spore wall (sensu Fungi)CC 8e-050.00587 GO:0030915Smc5-Smc6 complexCC 8e-050.00587 GO:0031160spore wallCC 8e-050.00587 GO:0042176regulation of protein catabolismBP 0.000260.00586 GO:0006376mRNA splice site selectionBP 0.000260.00586 GO:0045913positive regulation of carbohydrate metabolismBP 0.000260.00586 GO:0030150protein import into mitochondrial matrixBP 0.000870.00577 GO:0046489phosphoinositide biosynthesisBP 0.000870.00571 GO:0008081phosphoric diester hydrolase activityMF 0.000280.00571 GO:0051051negative regulation of transportBP 0.000260.00555 GO:0000735removal of nonhomologous endsBP 0.000260.00555 GO:0009251glucan catabolismBP 0.000260.00555 GO:0005724nuclear telomeric heterochromatinCC 7e-050.00554 GO:0005720nuclear heterochromatinCC 7e-050.00554 GO:0000346transcription export complexCC 7e-050.00554 GO:0000307cyclin-dependent protein kinase holoenzyme complexCC 7e-050.00554 GO:0031933telomeric heterochromatinCC 7e-050.00554 GO:0000792heterochromatinCC 7e-050.00554 GO:0043162ubiquitin-dependent protein catabolism via the multivesicular body pathwayBP 0.000850.00554 GO:0044272sulfur compound biosynthesisBP 0.000850.00554 GO:0004549tRNA-specific ribonuclease activityMF 0.000270.00553 GO:0006505GPI anchor metabolismBP 0.000850.00552 GO:0015718monocarboxylic acid transportBP 0.000260.00549 GO:0000055ribosomal large subunit export from nucleusBP 0.000260.00549 GO:0016514SWI/SNF complexCC 0.000370.00548 GO:0010008endosome membraneCC 0.000370.00548 GO:0044440endosomal partCC 0.000370.00548 GO:0009067aspartate family amino acid biosynthesisBP 0.000840.00547 GO:0015179L-amino acid transporter activityMF 0.000260.00546 GO:0016891endoribonuclease activity, producing 5'-phosphomonoestersMF 0.000250.00546 GO:0016471hydrogen-translocating V-type ATPase complexCC 0.000370.00544 GO:0006972hyperosmotic responseBP 0.000260.00544 GO:0017022myosin bindingMF 0.000160.00541 GO:0008559xenobiotic-transporting ATPase activityMF 0.000160.00541 GO:0042910xenobiotic transporter activityMF 0.000160.00541 GO:0004930G-protein coupled receptor activityMF 0.000160.00541 GO:0009199ribonucleoside triphosphate metabolismBP 0.000830.00537 GO:0009201ribonucleoside triphosphate biosynthesisBP 0.000830.00537 GO:0009141nucleoside triphosphate metabolismBP 0.000820.00535 GO:0004312fatty-acid synthase activityMF 0.000150.00533 GO:0016780phosphotransferase activity, for other substituted phosphate groupsMF 0.000240.00532 GO:0006506GPI anchor biosynthesisBP 0.000820.00531 GO:0006826iron ion transportBP 0.000820.00531 GO:0006206pyrimidine base metabolismBP 0.000820.00531 GO:0030847transcription termination from Pol II promoter, RNA polymerase(A)-independentBP 0.000250.00521 GO:0031126snoRNA 3'-end processingBP 0.000250.00521 GO:0009206purine ribonucleoside triphosphate biosynthesisBP 0.000810.0052 GO:0009142nucleoside triphosphate biosynthesisBP 0.000810.0052 GO:0009145purine nucleoside triphosphate biosynthesisBP 0.000810.0052 GO:0009205purine ribonucleoside triphosphate metabolismBP 0.000810.0052 GO:0045053protein retention in GolgiBP 0.000810.0052 GO:0009144purine nucleoside triphosphate metabolismBP 0.000810.0052 GO:0015986ATP synthesis coupled proton transportBP 0.00080.00515 GO:0046034ATP metabolismBP 0.00080.00515 GO:0006753nucleoside phosphate metabolismBP 0.00080.00515 GO:0006754ATP biosynthesisBP 0.00080.00515 GO:0015985energy coupled proton transport, down electrochemical gradientBP 0.00080.00515 GO:0016566specific transcriptional repressor activityMF 0.000230.00514 GO:0007020microtubule nucleationBP 0.00080.00513 GO:0051300spindle pole body organization and biogenesisBP 0.00080.00511 GO:0031023microtubule organizing center organization and biogenesisBP 0.00080.00511 GO:0030474spindle pole body duplicationBP 0.00080.00511 GO:0046933hydrogen-transporting ATP synthase activity, rotational mechanismMF 0.000220.00504 GO:0012501programmed cell deathBP 0.000250.00501 GO:0019722calcium-mediated signalingBP 0.000250.00501 GO:0016265deathBP 0.000250.00501 GO:0008219cell deathBP 0.000250.00501 GO:0006915apoptosisBP 0.000250.00501 GO:0005849mRNA cleavage factor complexCC 0.000350.00498 GO:0019220regulation of phosphate metabolismBP 0.000250.00498 GO:0051174regulation of phosphorus metabolismBP 0.000250.00498 GO:0008509anion transporter activityMF 0.000210.00496 GO:0006081aldehyde metabolismBP 0.000770.00491 GO:0045324late endosome to vacuole transportBP 0.000770.0049 GO:0003777microtubule motor activityMF 0.000150.0049 GO:0004620phospholipase activityMF 0.000150.0049 GO:0005095GTPase inhibitor activityMF 0.000150.0049 GO:0009295nucleoidCC 0.000340.00487 GO:0042645mitochondrial nucleoidCC 0.000340.00487 GO:0005686snRNP U2CC 0.000340.00487 GO:0031010ISWI complexCC 7e-050.00485 GO:0032299ribonuclease H2 complexCC 7e-050.00485 GO:0000407pre-autophagosomal structureCC 7e-050.00485 GO:0016587ISW1 complexCC 7e-050.00485 GO:0046112nucleobase biosynthesisBP 0.000760.00484 GO:0003720telomerase activityMF 0.000140.0048 GO:0006020myo-inositol metabolismBP 0.000250.00479 GO:0006828manganese ion transportBP 0.000250.00479 GO:0007103spindle pole body duplication in nuclear envelopeBP 0.000750.00477 GO:0016973poly(A)+ mRNA export from nucleusBP 0.000250.00473 GO:0006415translational terminationBP 0.000250.00473 GO:0006891intra-Golgi vesicle-mediated transportBP 0.000740.00473 GO:0005677chromatin silencing complexCC 7e-050.00472 GO:0051087chaperone bindingMF 0.000190.00472 GO:0006614SRP-dependent cotranslational protein targeting to membraneBP 0.000740.0047 GO:0005980glycogen catabolismBP 0.000240.00468 GO:0015399primary active transporter activityMF 0.000190.00466 GO:0015405P-P-bond-hydrolysis-driven transporter activityMF 0.000190.00466 GO:0006067ethanol metabolismBP 0.000730.00464 GO:0006999nuclear pore organization and biogenesisBP 0.000730.00464 GO:0008017microtubule bindingMF 0.000140.00462 GO:0005186pheromone activityMF 0.000140.00462 GO:0005102receptor bindingMF 0.000140.00462 GO:0000772mating pheromone activityMF 0.000140.00462 GO:0008320protein carrier activityMF 0.000140.00462 GO:0015174basic amino acid transporter activityMF 0.000140.00462 GO:0006895Golgi to endosome transportBP 0.000720.00461 GO:0016209antioxidant activityMF 0.000180.00461 GO:0019783small conjugating protein-specific protease activityMF 0.000180.00457 GO:0005525GTP bindingMF 0.000180.00457 GO:0004722protein serine/threonine phosphatase activityMF 0.000180.00457 GO:0015103inorganic anion transporter activityMF 0.000180.00457 GO:0015175neutral amino acid transporter activityMF 0.000140.00456 GO:0015893drug transportBP 0.000710.00455 GO:0006096glycolysisBP 0.00070.0045 GO:0003709RNA polymerase III transcription factor activityMF 0.000130.00448 GO:0016423tRNA (guanine) methyltransferase activityMF 0.000130.00447 GO:0006374nuclear mRNA splicing via U2-type spliceosomeBP 0.000690.00445 GO:0005485v-SNARE activityMF 0.000170.00443 GO:0006525arginine metabolismBP 0.000690.00443 GO:0000051urea cycle intermediate metabolismBP 0.000690.00443 GO:0006110regulation of glycolysisBP 0.000240.00442 GO:0000220hydrogen-transporting ATPase V0 domainCC 7e-050.00441 GO:0030026manganese ion homeostasisBP 0.000240.00438 GO:0005548phospholipid transporter activityMF 0.000160.00437 GO:0019001guanyl nucleotide bindingMF 0.000160.00433 GO:0006407rRNA export from nucleusBP 0.000670.00433 GO:0051029rRNA transportBP 0.000670.00433 GO:0045990regulation of transcription by carbon catabolitesBP 0.000240.0043 GO:0043167ion bindingMF 0.000150.00428 GO:0046961hydrogen-transporting ATPase activity, rotational mechanismMF 0.000150.00428 GO:0046872metal ion bindingMF 0.000150.00428 GO:0006609mRNA-binding (hnRNP) protein import into nucleusBP 0.000660.00428 GO:0030137COPI-coated vesicleCC 0.000310.00428 GO:0005801Golgi cis faceCC 0.000340.00428 GO:0000788nuclear nucleosomeCC 0.000310.00428 GO:0000932cytoplasmic mRNA processing bodyCC 0.000320.00428 GO:0000786nucleosomeCC 0.000310.00428 GO:0000146microfilament motor activityMF 0.000130.00427 GO:0000217DNA secondary structure bindingMF 0.000130.00427 GO:0042440pigment metabolismBP 0.000650.00425 GO:0019843rRNA bindingMF 0.000150.00424 GO:0006409tRNA export from nucleusBP 0.000650.00422 GO:0051031tRNA transportBP 0.000650.00422 GO:0009081branched chain family amino acid metabolismBP 0.000650.00421 GO:0043169cation bindingMF 0.000140.00419 GO:0019829cation-transporting ATPase activityMF 0.000150.00419 GO:0019748secondary metabolismBP 0.000640.00417 GO:0019237centromeric DNA bindingMF 0.000120.00417 GO:0006739NADP metabolismBP 0.000640.00416 GO:0006608snRNP protein import into nucleusBP 0.000630.00414 GO:0006607NLS-bearing substrate import into nucleusBP 0.000630.00414 GO:0006610ribosomal protein import into nucleusBP 0.000630.00414 GO:0006408snRNA export from nucleusBP 0.000630.00414 GO:0051030snRNA transportBP 0.000630.00414 GO:0000154rRNA modificationBP 0.000630.00413 GO:0045946positive regulation of translationBP 0.000240.00412 GO:0045727positive regulation of protein biosynthesisBP 0.000240.00412 GO:0031328positive regulation of cellular biosynthesisBP 0.000240.00412 GO:0009891positive regulation of biosynthesisBP 0.000240.00412 GO:0046148pigment biosynthesisBP 0.000630.00412 GO:0005279amino acid-polyamine transporter activityMF 0.000140.00411 GO:00001753'-5'-exoribonuclease activityMF 0.000140.00411 GO:0007006mitochondrial membrane organization and biogenesisBP 0.000620.0041 GO:0031011INO80 complexCC 0.00030.00409 GO:0005744mitochondrial inner membrane presequence translocase complexCC 0.00030.00409 GO:0016769transferase activity, transferring nitrogenous groupsMF 0.000130.00409 GO:0008483transaminase activityMF 0.000130.00409 GO:0007329positive regulation of transcription from RNA polymerase II promoter by pheromonesBP 0.000230.00406 GO:0009371positive regulation of transcription by pheromonesBP 0.000230.00406 GO:0006314intron homingBP 0.000230.00406 GO:0004840ubiquitin conjugating enzyme activityMF 0.000130.00406 GO:0000176nuclear exosome (RNase complex)CC 0.000290.00403 GO:0046540U4/U6 x U5 tri-snRNP complexCC 0.000290.00403 GO:0006379mRNA cleavageBP 0.000590.00401 GO:0050839cell adhesion molecule bindingMF 0.000110.004 GO:00431395' to 3' DNA helicase activityMF 0.000110.004 GO:0008237metallopeptidase activityMF 0.000120.004 GO:0009082branched chain family amino acid biosynthesisBP 0.000590.00399 GO:0006555methionine metabolismBP 0.000590.00398 GO:0009072aromatic amino acid family metabolismBP 0.000590.00398 GO:0050291sphingosine N-acyltransferase activityMF 0.000110.00397 GO:0004004ATP-dependent RNA helicase activityMF 0.000120.00397 GO:0032266phosphatidylinositol 3-phosphate bindingMF 0.000120.00397 GO:0015203polyamine transporter activityMF 0.000120.00397 GO:0019856pyrimidine base biosynthesisBP 0.000580.00396 GO:0003746translation elongation factor activityMF 0.000120.00395 GO:0016667oxidoreductase activity, acting on sulfur group of donorsMF 0.000120.00395 GO:0015698inorganic anion transportBP 0.000580.00395 GO:0006820anion transportBP 0.000570.00393 GO:0005742mitochondrial outer membrane translocase complexCC 7e-050.00393 GO:0016580Sin3 complexCC 7e-050.00393 GO:0005981regulation of glycogen catabolismBP 0.000230.00392 GO:0016684oxidoreductase activity, acting on peroxide as acceptorMF 0.000110.00388 GO:0015114phosphate transporter activityMF 0.00010.00388 GO:0004601peroxidase activityMF 0.000110.00388 GO:0042149cellular response to glucose starvationBP 0.000230.00385 GO:0006084acetyl-CoA metabolismBP 0.000540.00385 GO:0005746mitochondrial electron transport chainCC 0.000270.00384 GO:0009065glutamine family amino acid catabolismBP 0.000530.00381 GO:0006384transcription initiation from RNA polymerase III promoterBP 0.000520.00378 GO:0009069serine family amino acid metabolismBP 0.000520.00378 GO:0016860intramolecular oxidoreductase activityMF 0.000110.00376 GO:0016866intramolecular transferase activityMF 0.000110.00376 GO:0000026alpha-1,2-mannosyltransferase activityMF 0.00010.00376 GO:0000400four-way junction DNA bindingMF 0.00010.00376 GO:0030665clathrin coated vesicle membraneCC 0.000260.00373 GO:0005736DNA-directed RNA polymerase I complexCC 0.000260.00373 GO:0031234extrinsic to internal side of plasma membraneCC 7e-050.00372 GO:0001400mating projection baseCC 7e-050.00372 GO:0031931TORC 1 complexCC 7e-050.00372 GO:0005671Ada2/Gcn5/Ada3 transcription activator complexCC 7e-050.00372 GO:0009898internal side of plasma membraneCC 7e-050.00372 GO:0042401biogenic amine biosynthesisBP 0.00050.00371 GO:0007571age-dependent general metabolic declineBP 0.000230.0037 GO:0006734NADH metabolismBP 0.000490.00367 GO:0007007inner mitochondrial membrane organization and biogenesisBP 0.000480.00366 GO:0015914phospholipid transportBP 0.000470.00364 GO:0000114G1-specific transcription in mitotic cell cycleBP 0.000480.00364 GO:0042398amino acid derivative biosynthesisBP 0.000470.00363 GO:0006740NADPH regenerationBP 0.000470.00362 GO:0005545phosphatidylinositol bindingMF 9e-050.00361 GO:0045129NAD-independent histone deacetylase activityMF 9e-050.00361 GO:0019200carbohydrate kinase activityMF 9e-050.0036 GO:0009116nucleoside metabolismBP 0.000460.0036 GO:0016455RNA polymerase II transcription mediator activityMF 8e-050.00359 GO:0000105histidine biosynthesisBP 0.000450.00359 GO:0009075histidine family amino acid metabolismBP 0.000450.00359 GO:0009084glutamine family amino acid biosynthesisBP 0.000450.00359 GO:0006547histidine metabolismBP 0.000450.00359 GO:0009076histidine family amino acid biosynthesisBP 0.000450.00359 GO:0000915cytokinesis, contractile ring formationBP 0.000230.00358 GO:0000912cytokinesis, formation of actomyosin apparatusBP 0.000230.00358 GO:0031032actomyosin structure organization and biogenesisBP 0.000230.00358 GO:0031306intrinsic to mitochondrial outer membraneCC 0.000250.00357 GO:0030684preribosomeCC 0.000250.00357 GO:0031307integral to mitochondrial outer membraneCC 0.000250.00357 GO:0009452RNA cappingBP 0.000220.00356 GO:0016859cis-trans isomerase activityMF 8e-050.00356 GO:0003755peptidyl-prolyl cis-trans isomerase activityMF 8e-050.00356 GO:0030685nucleolar preribosomeCC 0.000240.00351 GO:0005828kinetochore microtubuleCC 0.000240.00351 GO:0008238exopeptidase activityMF 7e-050.00349 GO:0019674NAD metabolismBP 0.000410.00349 GO:0042773ATP synthesis coupled electron transportBP 0.00040.00348 GO:0042775ATP synthesis coupled electron transport (sensu Eukaryota)BP 0.00040.00348 GO:0004222metalloendopeptidase activityMF 7e-050.00346 GO:0001401mitochondrial sorting and assembly machinery complexCC 7e-050.00346 GO:0051187cofactor catabolismBP 0.000380.00344 GO:0006116NADH oxidationBP 0.000370.00343 GO:0015295solute:hydrogen symporter activityMF 9e-050.00341 GO:0008143poly(A) bindingMF 9e-050.00341 GO:0003727single-stranded RNA bindingMF 9e-050.00341 GO:0050874organismal physiological processBP 0.000220.00341 GO:0007600sensory perceptionBP 0.000220.00341 GO:0050877neurophysiological processBP 0.000220.00341 GO:0007606sensory perception of chemical stimulusBP 0.000220.00341 GO:0051869physiological response to stimulusBP 0.000220.00341 GO:0035251UDP-glucosyltransferase activityMF 6e-050.0034 GO:0016645oxidoreductase activity, acting on the CH-NH group of donorsMF 6e-050.0034 GO:0000302response to reactive oxygen speciesBP 0.000360.00339 GO:0006099tricarboxylic acid cycleBP 0.000360.00339 GO:0046356acetyl-CoA catabolismBP 0.000360.00339 GO:0015802basic amino acid transportBP 0.000220.00338 GO:0000178exosome (RNase complex)CC 0.000230.00337 GO:0046914transition metal ion bindingMF 6e-050.00336 GO:0046527glucosyltransferase activityMF 6e-050.00336 GO:0016814hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidinesMF 6e-050.00336 GO:0004843ubiquitin-specific protease activityMF 6e-050.00336 GO:0009070serine family amino acid biosynthesisBP 0.000340.00336 GO:0051119sugar transporter activityMF 6e-050.00334 GO:0006537glutamate biosynthesisBP 0.000320.00334 GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygenMF 8e-050.00332 GO:0003701RNA polymerase I transcription factor activityMF 8e-050.00332 GO:0001671ATPase stimulator activityMF 9e-050.00332 GO:0004526ribonuclease P activityMF 9e-050.00332 GO:0000099sulfur amino acid transporter activityMF 9e-050.00332 GO:0030489processing of 27S pre-rRNABP 0.000310.00332 GO:0006207'de novo' pyrimidine base biosynthesisBP 0.000310.00332 GO:0006816calcium ion transportBP 0.000220.00331 GO:0003689DNA clamp loader activityMF 8e-050.0033 GO:0009073aromatic amino acid family biosynthesisBP 0.00030.00329 GO:0019438aromatic compound biosynthesisBP 0.00030.00329 GO:0030261chromosome condensationBP 0.000290.00329 GO:0000390spliceosome disassemblyBP 0.000220.00328 GO:0000391U2-type spliceosome disassemblyBP 0.000220.00328 GO:0045454cell redox homeostasisBP 0.000280.00328 GO:0031109microtubule polymerization or depolymerizationBP 0.000280.00328 GO:0030503regulation of cell redox homeostasisBP 0.000280.00328 GO:0016646oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptorMF 5e-050.00327 GO:0042168heme metabolismBP 0.000270.00327 GO:0006778porphyrin metabolismBP 0.000270.00327 GO:0015230FAD transporter activityMF 8e-050.00326 GO:0009109coenzyme catabolismBP 0.000260.00325 GO:0043038amino acid activationBP 0.000250.00323 GO:0006418tRNA aminoacylation for protein translationBP 0.000250.00323 GO:0043039tRNA aminoacylationBP 0.000250.00323 GO:0030258lipid modificationBP 0.000250.00323 GO:0006100tricarboxylic acid cycle intermediate metabolismBP 0.000250.00323 GO:0042721mitochondrial inner membrane protein insertion complexCC 7e-050.00322 GO:0005697telomerase holoenzyme complexCC 7e-050.00322 GO:0006536glutamate metabolismBP 0.000240.00321 GO:0009123nucleoside monophosphate metabolismBP 0.000220.0032 GO:0019395fatty acid oxidationBP 0.000210.00318 GO:0016675oxidoreductase activity, acting on heme group of donorsMF 4e-050.00318 GO:0016676oxidoreductase activity, acting on heme group of donors, oxygen as acceptorMF 4e-050.00318 GO:0004129cytochrome-c oxidase activityMF 4e-050.00318 GO:0019239deaminase activityMF 4e-050.00318 GO:0015002heme-copper terminal oxidase activityMF 4e-050.00318 GO:0009127purine nucleoside monophosphate biosynthesisBP 0.000190.00316 GO:0005261cation channel activityMF 8e-050.00315 GO:0005825half bridge of spindle pole bodyCC 6e-050.00314 GO:0000145exocystCC 6e-050.00314 GO:0000184mRNA catabolism, nonsense-mediated decayBP 0.000210.00314 GO:0048285organelle fissionBP 0.000210.00314 GO:0043130ubiquitin bindingMF 8e-050.00313 GO:0016638oxidoreductase activity, acting on the CH-NH2 group of donorsMF 8e-050.00313 GO:0004177aminopeptidase activityMF 3e-050.00312 GO:0008374O-acyltransferase activityMF 3e-050.00312 GO:0000348nuclear mRNA branch site recognitionBP 0.000210.0031 GO:0016892endoribonuclease activity, producing 3'-phosphomonoestersMF 8e-050.0031 GO:0000213tRNA-intron endonuclease activityMF 8e-050.0031 GO:0003684damaged DNA bindingMF 8e-050.0031 GO:0009126purine nucleoside monophosphate metabolismBP 0.000150.00309 GO:0006098pentose-phosphate shuntBP 0.000150.00309 GO:0005262calcium channel activityMF 7e-050.00308 GO:0006783heme biosynthesisBP 0.000140.00308 GO:0009161ribonucleoside monophosphate metabolismBP 0.000140.00308 GO:0009124nucleoside monophosphate biosynthesisBP 0.000140.00308 GO:0009167purine ribonucleoside monophosphate metabolismBP 0.000140.00308 GO:0006779porphyrin biosynthesisBP 0.000140.00308 GO:0016831carboxy-lyase activityMF 3e-050.00308 GO:0004725protein tyrosine phosphatase activityMF 3e-050.00308 GO:0017196N-terminal peptidyl-methionine acetylationBP 0.000210.00307 GO:0018206peptidyl-methionine modificationBP 0.000210.00307 GO:0000243commitment complexCC 0.000190.00304 GO:0030118clathrin coatCC 0.00020.00304 GO:0030125clathrin vesicle coatCC 0.00020.00304 GO:0005682snRNP U5CC 0.000210.00304 GO:0005689minor (U12-dependent) spliceosome complexCC 0.000210.00304 GO:0005666DNA-directed RNA polymerase III complexCC 0.000190.00304 GO:0005665DNA-directed RNA polymerase II, core complexCC 0.000190.00304 GO:0031110regulation of microtubule polymerization or depolymerizationBP 0.000110.00303 GO:0000372Group I intron splicingBP 0.000210.00302 GO:0000019regulation of mitotic recombinationBP 0.000210.00302 GO:0018205peptidyl-lysine modificationBP 0.000210.00302 GO:0000376RNA splicing, via transesterification reactions with guanosine as nucleophileBP 0.000210.00302 GO:0016894endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoestersMF 7e-050.00302 GO:0016274protein-arginine N-methyltransferase activityMF 7e-050.00302 GO:0016273arginine N-methyltransferase activityMF 7e-050.00302 GO:0016628oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptorMF 7e-050.00302 GO:0031163metallo-sulfur cluster assemblyBP 6e-050.003 GO:0006189'de novo' IMP biosynthesisBP 6e-050.003 GO:0009156ribonucleoside monophosphate biosynthesisBP 6e-050.003 GO:0046040IMP metabolismBP 6e-050.003 GO:0009168purine ribonucleoside monophosphate biosynthesisBP 6e-050.003 GO:0016226iron-sulfur cluster assemblyBP 6e-050.003 GO:0006188IMP biosynthesisBP 6e-050.003 GO:0042180ketone metabolismBP 0.000210.00299 GO:0005832chaperonin-containing T-complexCC 0.000180.00298 GO:0006458'de novo' protein foldingBP 0.000210.00294 GO:0000092mitotic anaphase BBP 0.000210.00294 GO:0008053mitochondrial fusionBP 0.000210.00294 GO:0005353fructose transporter activityMF 00.00289 GO:0015149hexose transporter activityMF 00.00289 GO:0030276clathrin bindingMF 1e-050.00289 GO:0015145monosaccharide transporter activityMF 00.00289 GO:0015662ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanismMF 00.00289 GO:0005355glucose transporter activityMF 00.00289 GO:0016830carbon-carbon lyase activityMF 1e-050.00289 GO:0015036disulfide oxidoreductase activityMF 00.00289 GO:0004659prenyltransferase activityMF 00.00289 GO:0016722oxidoreductase activity, oxidizing metal ionsMF 00.00289 GO:0015578mannose transporter activityMF 00.00289 GO:0016073snRNA metabolismBP 0.000210.00287 GO:0045821positive regulation of glycolysisBP 0.000210.00287 GO:0015932nucleobase, nucleoside, nucleotide and nucleic acid transporter activityMF 7e-050.00287 GO:0042134rRNA primary transcript bindingMF 7e-050.00287 GO:0000255allantoin metabolismBP 0.00020.00286 GO:0006279premeiotic DNA synthesisBP 0.00020.00286 GO:0000256allantoin catabolismBP 0.00020.00286 GO:0046700heterocycle catabolismBP 0.00020.00286 GO:0015079potassium ion transporter activityMF 7e-050.00284 GO:0006562proline catabolismBP 0.00020.00284 GO:0006359regulation of transcription from RNA polymerase III promoterBP 0.00020.00284 GO:0005845mRNA cap complexCC 6e-050.0028 GO:0006672ceramide metabolismBP 0.00020.00279 GO:0045040protein import into mitochondrial outer membraneBP 0.00020.00278 GO:0000266mitochondrial fissionBP 0.00020.00277 GO:0005791rough endoplasmic reticulumCC 0.000110.00275 GO:0030119membrane coat adaptor complexCC 0.000120.00275 GO:0030867rough endoplasmic reticulum membraneCC 0.000110.00275 GO:0005669transcription factor TFIID complexCC 0.000140.00275 GO:0005751respiratory chain complex IV (sensu Eukaryota)CC 0.000130.00275 GO:0000119mediator complexCC 0.000160.00275 GO:0045277respiratory chain complex IVCC 0.000130.00275 GO:0045263proton-transporting ATP synthase complex, coupling factor F(o)CC 0.00010.00274 GO:0000276proton-transporting ATP synthase complex, coupling factor F(o) (sensu Eukaryota)CC 0.00010.00274 GO:0016884carbon-nitrogen ligase activity, with glutamine as amido-N-donorMF 6e-050.00274 GO:0015359amino acid permease activityMF 6e-050.00274 GO:0005384manganese ion transporter activityMF 6e-050.00272 GO:0006855multidrug transportBP 0.00020.00271 GO:0007089traversing start control point of mitotic cell cycleBP 0.00020.00271 GO:0008278cohesin complexCC 6e-050.0027 GO:0005775vacuolar lumenCC 6e-050.0027 GO:0000299integral to membrane of membrane fractionCC 6e-050.0027 GO:0000798nuclear cohesin complexCC 6e-050.0027 GO:0006829zinc ion transportBP 0.00020.00268 GO:0030414protease inhibitor activityMF 6e-050.00268 GO:0015173aromatic amino acid transporter activityMF 6e-050.00264 GO:0005685snRNP U1CC 7e-050.00261 GO:0008177succinate dehydrogenase (ubiquinone) activityMF 6e-050.00261 GO:0016635oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptorMF 6e-050.00261 GO:0005315inorganic phosphate transporter activityMF 6e-050.00261 GO:0019751polyol metabolismBP 0.000190.00261 GO:0006071glycerol metabolismBP 0.000190.00261 GO:0045039protein import into mitochondrial inner membraneBP 0.000190.00261 GO:0043141ATP-dependent 5' to 3' DNA helicase activityMF 6e-050.0026 GO:0005486t-SNARE activityMF 5e-050.00257 GO:0006656phosphatidylcholine biosynthesisBP 0.000190.00257 GO:0006817phosphate transportBP 0.000190.00255 GO:0042274ribosomal small subunit biogenesisBP 0.000190.00248 GO:0005338nucleotide-sugar transporter activityMF 5e-050.00245 GO:0005286basic amino acid permease activityMF 5e-050.00245 GO:0003923GPI-anchor transamidase activityMF 5e-050.00245 GO:0016679oxidoreductase activity, acting on diphenols and related substances as donorsMF 5e-050.00244 GO:0005851eukaryotic translation initiation factor 2B complexCC 6e-050.00244 GO:0000214tRNA-intron endonuclease complexCC 6e-050.00244 GO:0018456aryl-alcohol dehydrogenase activityMF 5e-050.00244 GO:0000328vacuolar lumen (sensu Fungi)CC 6e-050.00244 GO:0005824outer plaque of spindle pole bodyCC 6e-050.00244 GO:0000108repairosomeCC 6e-050.00244 GO:0000172ribonuclease MRP complexCC 6e-050.00244 GO:0008121ubiquinol-cytochrome-c reductase activityMF 5e-050.00244 GO:0016681oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptorMF 5e-050.00244 GO:0042981regulation of apoptosisBP 0.000190.00242 GO:0030242peroxisome degradationBP 0.000190.00242 GO:0043067regulation of programmed cell deathBP 0.000190.00242 GO:0000393spliceosomal conformational changes to generate catalytic conformationBP 0.000190.00242 GO:0016790thiolester hydrolase activityMF 5e-050.00241 GO:0035004phosphoinositide 3-kinase activityMF 5e-050.00241 GO:0000268peroxisome targeting sequence bindingMF 5e-050.00241 GO:0015247aminophospholipid transporter activityMF 5e-050.00236 GO:0004012phospholipid-translocating ATPase activityMF 5e-050.00236 GO:0048037cofactor bindingMF 5e-050.00236 GO:0019238cyclohydrolase activityMF 5e-050.00236 GO:0001405presequence translocase-associated import motorCC 6e-050.00235 GO:0044242cellular lipid catabolismBP 0.000180.00233 GO:0016042lipid catabolismBP 0.000180.00233 GO:0016882cyclo-ligase activityMF 4e-050.00232 GO:0008443phosphofructokinase activityMF 4e-050.00232 GO:0045143homologous chromosome segregationBP 0.000180.00231 GO:0006551leucine metabolismBP 0.000180.00231 GO:0007532regulation of transcription, mating-type specificBP 0.000180.00231 GO:0046323glucose importBP 0.000180.00231 GO:0008422beta-glucosidase activityMF 4e-050.0023 GO:0004338glucan 1,3-beta-glucosidase activityMF 4e-050.0023 GO:0051348negative regulation of transferase activityBP 0.000180.00229 GO:0006469negative regulation of protein kinase activityBP 0.000180.00229 GO:0000500RNA polymerase I upstream activating factor complexCC 5e-050.00224 GO:0042326negative regulation of phosphorylationBP 0.000170.00224 GO:0042325regulation of phosphorylationBP 0.000170.00224 GO:0045936negative regulation of phosphate metabolismBP 0.000170.00224 GO:0016725oxidoreductase activity, acting on CH2 groupsMF 4e-050.00223 GO:0000715nucleotide-excision repair, DNA damage recognitionBP 0.000170.00223 GO:0043021ribonucleoprotein bindingMF 4e-050.0022 GO:0016339calcium-dependent cell-cell adhesionBP 0.000170.00218 GO:0000501flocculation via cell wall protein-carbohydrate interactionBP 0.000170.00218 GO:0000128flocculationBP 0.000170.00218 GO:0007008outer mitochondrial membrane organization and biogenesisBP 0.000170.00217 GO:0009085lysine biosynthesisBP 0.000170.00217 GO:0046173polyol biosynthesisBP 0.000170.00217 GO:0043044ATP-dependent chromatin remodelingBP 0.000170.00217 GO:0046513ceramide biosynthesisBP 0.000170.00217 GO:0006553lysine metabolismBP 0.000170.00217 GO:0043486histone exchangeBP 0.000170.00217 GO:0046520sphingoid biosynthesisBP 0.000170.00217 GO:0006114glycerol biosynthesisBP 0.000170.00217 GO:0006446regulation of translational initiationBP 0.000170.00215 GO:0000729DNA double-strand break processingBP 0.000170.00215 GO:0000738DNA catabolism, exonucleolyticBP 0.000170.00215 GO:0000706meiotic DNA double-strand break processingBP 0.000170.00215 GO:0009102biotin biosynthesisBP 0.000170.00213 GO:0006768biotin metabolismBP 0.000170.00213 GO:0006616SRP-dependent cotranslational protein targeting to membrane, translocationBP 0.000160.00211 GO:0042393histone bindingMF 4e-050.0021 GO:0051377mannose-ethanolamine phosphotransferase activityMF 4e-050.0021 GO:0004497monooxygenase activityMF 4e-050.0021 GO:0016776phosphotransferase activity, phosphate group as acceptorMF 4e-050.0021 GO:0016668oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptorMF 4e-050.0021 GO:0031930mitochondrial signaling pathwayBP 0.000160.00209 GO:0008379thioredoxin peroxidase activityMF 3e-050.00205 GO:00038431,3-beta-glucan synthase activityMF 3e-050.00205 GO:0006083acetate metabolismBP 0.000160.00202 GO:0031386protein tagMF 3e-050.00202 GO:0045896regulation of transcription, mitoticBP 0.000160.002 GO:0007068negative regulation of transcription, mitoticBP 0.000160.002 GO:0019660glycolytic fermentationBP 0.000150.00197 GO:0000349formation of catalytic spliceosome for first transesterification stepBP 0.000150.00196 GO:0019878lysine biosynthesis via aminoadipic acidBP 0.000150.00195 GO:0016530metallochaperone activityMF 3e-050.00194 GO:0016413O-acetyltransferase activityMF 3e-050.00194 GO:0005097Rab GTPase activator activityMF 3e-050.00194 GO:0004738pyruvate dehydrogenase activityMF 3e-050.00194 GO:0005507copper ion bindingMF 3e-050.00194 GO:0016833oxo-acid-lyase activityMF 3e-050.00194 GO:0005385zinc ion transporter activityMF 3e-050.00194 GO:0004739pyruvate dehydrogenase (acetyl-transferring) activityMF 3e-050.00194 GO:0030371translation repressor activityMF 3e-050.00194 GO:0006449regulation of translational terminationBP 0.000150.00193 GO:0007025beta-tubulin foldingBP 0.000150.00193 GO:0016624oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptorMF 3e-050.0019 GO:0015791polyol transportBP 0.000140.00189 GO:0051054positive regulation of DNA metabolismBP 0.000140.00188 GO:0015883FAD transportBP 0.000140.00187 GO:0000097sulfur amino acid biosynthesisBP 0.000140.00187 GO:0043001Golgi to plasma membrane protein transportBP 0.000140.00187 GO:0019203carbohydrate phosphatase activityMF 3e-050.00186 GO:0004576oligosaccharyl transferase activityMF 3e-050.00186 GO:0016846carbon-sulfur lyase activityMF 3e-050.00186 GO:0004579dolichyl-diphosphooligosaccharide-protein glycotransferase activityMF 3e-050.00186 GO:0006760folic acid and derivative metabolismBP 0.000140.00185 GO:0006390transcription from mitochondrial promoterBP 0.000140.00185 GO:0009098leucine biosynthesisBP 0.000140.00184 GO:0000385spliceosomal catalysisMF 2e-050.00182 GO:0030188chaperone regulator activityMF 2e-050.00182 GO:0005537mannose bindingMF 2e-050.00182 GO:0000386second spliceosomal transesterification activityMF 2e-050.00182 GO:0004866endopeptidase inhibitor activityMF 2e-050.00182 GO:0008252nucleotidase activityMF 2e-050.00182 GO:0000743nuclear migration during conjugation with cellular fusionBP 0.000140.00182 GO:0031578spindle orientation checkpointBP 0.000140.00182 GO:0016531copper chaperone activityMF 2e-050.0018 GO:0017171serine hydrolase activityMF 2e-050.0018 GO:0042710biofilm formationBP 0.000130.00179 GO:0016180snRNA processingBP 0.000130.00179 GO:0016558protein import into peroxisome matrixBP 0.000130.00179 GO:0007109cytokinesis, completion of separationBP 0.000130.00179 GO:0009409response to coldBP 0.000130.00178 GO:0042026protein refoldingBP 0.000130.00178 GO:0019439aromatic compound catabolismBP 0.000130.00176 GO:0005786signal recognition particle (sensu Eukaryota)CC 5e-050.00176 GO:0045283fumarate reductase complexCC 5e-050.00176 GO:0005941unlocalized protein complexCC 5e-050.00176 GO:0000126transcription factor TFIIIB complexCC 5e-050.00176 GO:0000113nucleotide-excision repair factor 4 complexCC 5e-050.00176 GO:0000417HIR complexCC 5e-050.00176 GO:0045273respiratory chain complex IICC 5e-050.00176 GO:0030131clathrin adaptor complexCC 5e-050.00176 GO:0043614multi-eIF complexCC 5e-050.00176 GO:0030126COPI vesicle coatCC 5e-050.00176 GO:0031225anchored to membraneCC 5e-050.00176 GO:0005852eukaryotic translation initiation factor 3 complexCC 5e-050.00176 GO:0005788endoplasmic reticulum lumenCC 5e-050.00176 GO:0012510trans-Golgi network transport vesicle membraneCC 5e-050.00176 GO:0000127transcription factor TFIIIC complexCC 5e-050.00176 GO:0000137Golgi cis cisternaCC 5e-050.00176 GO:0000347THO complexCC 5e-050.00176 GO:0005750respiratory chain complex III (sensu Eukaryota)CC 5e-050.00176 GO:0045257succinate dehydrogenase complex (ubiquinone)CC 5e-050.00176 GO:0045285ubiquinol-cytochrome-c reductase complexCC 5e-050.00176 GO:0048500signal recognition particleCC 5e-050.00176 GO:0042765GPI-anchor transamidase complexCC 5e-050.00176 GO:0045275respiratory chain complex IIICC 5e-050.00176 GO:0005675transcription factor TFIIH complexCC 5e-050.00176 GO:0031518CBF3 complexCC 5e-050.00176 GO:0046658anchored to plasma membraneCC 5e-050.00176 GO:0030663COPI coated vesicle membraneCC 5e-050.00176 GO:0005823central plaque of spindle pole bodyCC 5e-050.00176 GO:0005749respiratory chain complex II (sensu Eukaryota)CC 5e-050.00176 GO:0042720mitochondrial inner membrane peptidase complexCC 5e-050.00176 GO:0000813ESCRT I complexCC 5e-050.00176 GO:0045281succinate dehydrogenase complexCC 5e-050.00176 GO:0031205Sec complex (sensu Eukaryota)CC 5e-050.00176 GO:00001481,3-beta-glucan synthase complexCC 5e-050.00176 GO:0019655glucose catabolism to ethanolBP 0.000130.00174 GO:0006012galactose metabolismBP 0.000130.00174 GO:0006518peptide metabolismBP 0.000130.00174 GO:0000158protein phosphatase type 2A activityMF 2e-050.00174 GO:0019904protein domain specific bindingMF 2e-050.00174 GO:0017056structural constituent of nuclear poreMF 2e-050.00174 GO:0016861intramolecular oxidoreductase activity, interconverting aldoses and ketosesMF 2e-050.00174 GO:0031072heat shock protein bindingMF 2e-050.00174 GO:0005375copper ion transporter activityMF 2e-050.00174 GO:0015793glycerol transportBP 0.000120.00173 GO:0006827high affinity iron ion transportBP 0.000120.00173 GO:0006526arginine biosynthesisBP 0.000120.00173 GO:0001323age-dependent general metabolic decline during chronological cell agingBP 0.000120.0017 GO:0001306age-dependent response to oxidative stressBP 0.000120.0017 GO:0001324age-dependent response to oxidative stress during chronological cell agingBP 0.000120.0017 GO:0019413acetate biosynthesisBP 0.000120.00169 GO:0004022alcohol dehydrogenase activityMF 2e-050.00169 GO:0008079translation termination factor activityMF 2e-050.00169 GO:0004730pseudouridylate synthase activityMF 2e-050.00169 GO:0003747translation release factor activityMF 2e-050.00169 GO:0046185aldehyde catabolismBP 0.000120.00167 GO:0003916DNA topoisomerase activityMF 2e-050.00166 GO:0019794nonprotein amino acid metabolismBP 0.000120.00166 GO:0006882zinc ion homeostasisBP 0.000120.00166 GO:0006883sodium ion homeostasisBP 0.000120.00166 GO:0046015regulation of transcription by glucoseBP 0.000120.00166 GO:0000755cytogamyBP 0.000120.00166 GO:0046685response to arsenicBP 0.000120.00166 GO:0043405regulation of MAPK activityBP 0.000110.00165 GO:0030687nucleolar preribosome, large subunit precursorCC 5e-050.00164 GO:0005658alpha DNA polymerase:primase complexCC 5e-050.00164 GO:0016439tRNA-pseudouridine synthase activityMF 2e-050.00164 GO:0005498sterol carrier activityMF 2e-050.00164 GO:0005496steroid bindingMF 2e-050.00164 GO:0008142oxysterol bindingMF 2e-050.00164 GO:0015215nucleotide transporter activityMF 2e-050.00164 GO:0006566threonine metabolismBP 0.000110.00163 GO:0051261protein depolymerizationBP 0.000110.00163 GO:0045014negative regulation of transcription by glucoseBP 0.000110.00163 GO:0051668localization within membraneBP 0.000110.00163 GO:0015908fatty acid transportBP 0.000110.00163 GO:0015865purine nucleotide transportBP 0.000110.00163 GO:0045013negative regulation of transcription by carbon catabolitesBP 0.000110.00163 GO:0006465signal peptide processingBP 0.000110.00163 GO:0019935cyclic-nucleotide-mediated signalingBP 0.000110.00161 GO:0009396folic acid and derivative biosynthesisBP 0.000110.00161 GO:0019933cAMP-mediated signalingBP 0.000110.00161 GO:0017069snRNA bindingMF 2e-050.0016 GO:0008536Ran GTPase bindingMF 2e-050.0016 GO:0000774adenyl-nucleotide exchange factor activityMF 2e-050.0016 GO:0015197peptide transporter activityMF 2e-050.0016 GO:00038736-phosphofructo-2-kinase activityMF 2e-050.0016 GO:0016639oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptorMF 2e-050.0016 GO:0046912transferase activity, transferring acyl groups, acyl groups converted into alkyl on transferMF 2e-050.0016 GO:0017137Rab GTPase bindingMF 2e-050.0016 GO:0016255attachment of GPI anchor to proteinBP 0.000110.00159 GO:0015780nucleotide-sugar transportBP 0.000110.00159 GO:0031321prospore formationBP 0.000110.00159 GO:0030869RENT complexCC 4e-050.00158 GO:0008250oligosaccharyl transferase complexCC 4e-050.00158 GO:0006122mitochondrial electron transport, ubiquinol to cytochrome cBP 0.000110.00158 GO:0019795nonprotein amino acid biosynthesisBP 0.000110.00157 GO:0000101sulfur amino acid transportBP 0.00010.00154 GO:0006878copper ion homeostasisBP 0.00010.00154 GO:0006166purine ribonucleoside salvageBP 0.00010.00154 GO:0043174nucleoside salvageBP 0.00010.00154 GO:0007323peptide pheromone maturationBP 0.00010.00154 GO:0016289CoA hydrolase activityMF 1e-050.00152 GO:0003893epsilon DNA polymerase activityMF 1e-050.00152 GO:0020037heme bindingMF 1e-050.00152 GO:0005089Rho guanyl-nucleotide exchange factor activityMF 1e-050.00152 GO:0008649rRNA methyltransferase activityMF 1e-050.00152 GO:0046906tetrapyrrole bindingMF 1e-050.00152 GO:0006617SRP-dependent cotranslational protein targeting to membrane, signal sequence recognitionBP 0.00010.00152 GO:0006813potassium ion transportBP 0.00010.00152 GO:0006791sulfur utilizationBP 0.00010.00152 GO:0000103sulfate assimilationBP 0.00010.00152 GO:0005655nucleolar ribonuclease P complexCC 4e-050.00151 GO:0000796condensin complexCC 4e-050.00151 GO:0030677ribonuclease P complexCC 4e-050.00151 GO:0030681multimeric ribonuclease P complexCC 4e-050.00151 GO:0042597periplasmic spaceCC 4e-050.00151 GO:0008180signalosome complexCC 4e-050.00151 GO:0030287periplasmic space (sensu Fungi)CC 4e-050.00151 GO:0005853eukaryotic translation elongation factor 1 complexCC 4e-050.00151 GO:0000799nuclear condensin complexCC 4e-050.00151 GO:0043331response to dsRNABP 0.00010.0015 GO:0051707response to other organismBP 0.00010.0015 GO:0009615response to virusBP 0.00010.0015 GO:0006123mitochondrial electron transport, cytochrome c to oxygenBP 0.00010.0015 GO:0043330response to exogenous dsRNABP 0.00010.0015 GO:0051383kinetochore organization and biogenesisBP 9e-050.00148 GO:0009225nucleotide-sugar metabolismBP 9e-050.00148 GO:0051382kinetochore assemblyBP 9e-050.00148 GO:0006544glycine metabolismBP 9e-050.00148 GO:0008614pyridoxine metabolismBP 9e-050.00146 GO:0042816vitamin B6 metabolismBP 9e-050.00146 GO:0006085acetyl-CoA biosynthesisBP 9e-050.00146 GO:0004558alpha-glucosidase activityMF 1e-050.00145 GO:0004088carbamoyl-phosphate synthase (glutamine-hydrolyzing) activityMF 1e-050.00145 GO:0016783sulfurtransferase activityMF 1e-050.00145 GO:0016774phosphotransferase activity, carboxyl group as acceptorMF 1e-050.00145 GO:0016868intramolecular transferase activity, phosphotransferasesMF 1e-050.00145 GO:0031267small GTPase bindingMF 1e-050.00145 GO:0051020GTPase bindingMF 1e-050.00145 GO:0004086carbamoyl-phosphate synthase activityMF 1e-050.00145 GO:00084095'-3' exonuclease activityMF 1e-050.00145 GO:0016782transferase activity, transferring sulfur-containing groupsMF 1e-050.00145 GO:0004372glycine hydroxymethyltransferase activityMF 1e-050.00145 GO:0016854racemase and epimerase activityMF 1e-050.00145 GO:0017016Ras GTPase bindingMF 1e-050.00145 GO:0000150recombinase activityMF 1e-050.00145 GO:0005100Rho GTPase activator activityMF 1e-050.00145 GO:0000739DNA strand annealing activityMF 1e-050.00143 GO:0000120RNA polymerase I transcription factor complexCC 4e-050.00143 GO:0000811GINS complexCC 4e-050.00143 GO:0000159protein phosphatase type 2A complexCC 4e-050.00143 GO:0005967pyruvate dehydrogenase complex (sensu Eukaryota)CC 4e-050.00143 GO:0005946alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)CC 4e-050.00143 GO:0017102methionyl glutamyl tRNA synthetase complexCC 4e-050.00143 GO:0016281eukaryotic translation initiation factor 4F complexCC 4e-050.00143 GO:0016593Cdc73/Paf1 complexCC 4e-050.00143 GO:0045254pyruvate dehydrogenase complexCC 4e-050.00143 GO:0005850eukaryotic translation initiation factor 2 complexCC 4e-050.00143 GO:0005955calcineurin complexCC 4e-050.00143 GO:0045026plasma membrane fusionBP 9e-050.00142 GO:0031204posttranslational protein targeting to membrane, translocationBP 9e-050.00142 GO:0042727riboflavin and derivative biosynthesisBP 9e-050.00142 GO:0031532actin cytoskeleton reorganizationBP 9e-050.00142 GO:0030037actin filament reorganization during cell cycleBP 9e-050.00142 GO:0018065protein-cofactor linkageBP 9e-050.00142 GO:0042726riboflavin and derivative metabolismBP 9e-050.00142 GO:0043328protein targeting to vacuole during ubiquitin-dependent protein catabolism via the MVB pathwayBP 9e-050.00142 GO:0009068aspartate family amino acid catabolismBP 9e-050.00142 GO:0008283cell proliferationBP 9e-050.00142 GO:0001304progressive alteration of chromatin during replicative cell agingBP 9e-050.00142 GO:0007076mitotic chromosome condensationBP 9e-050.00139 GO:0006121mitochondrial electron transport, succinate to ubiquinoneBP 9e-050.00139 GO:0000370U2-type nuclear mRNA branch site recognitionBP 9e-050.00139 GO:0008655pyrimidine salvageBP 9e-050.00139 GO:0006491N-glycan processingBP 8e-050.00139 GO:0005984disaccharide metabolismBP 8e-050.00139 GO:0009268response to pHBP 8e-050.00139 GO:0015891siderophore transportBP 8e-050.00139 GO:0000009alpha-1,6-mannosyltransferase activityMF 1e-050.00136 GO:0008235metalloexopeptidase activityMF 1e-050.00136 GO:0004100chitin synthase activityMF 1e-050.00136 GO:0019206nucleoside kinase activityMF 1e-050.00136 GO:0047429nucleoside-triphosphate diphosphatase activityMF 1e-050.00136 GO:0004707MAP kinase activityMF 1e-050.00136 GO:0008270zinc ion bindingMF 1e-050.00136 GO:0000049tRNA bindingMF 1e-050.00136 GO:0004033aldo-keto reductase activityMF 1e-050.00136 GO:0004437inositol or phosphatidylinositol phosphatase activityMF 1e-050.00136 GO:0000171ribonuclease MRP activityMF 1e-050.00136 GO:0008897phosphopantetheinyltransferase activityMF 1e-050.00136 GO:0015297antiporter activityMF 1e-050.00136 GO:0009982pseudouridine synthase activityMF 1e-050.00136 GO:0016863intramolecular oxidoreductase activity, transposing C=C bondsMF 1e-050.00136 GO:0042802identical protein bindingMF 1e-050.00136 GO:0015085calcium ion transporter activityMF 1e-050.00136 GO:0019201nucleotide kinase activityMF 1e-050.00136 GO:0008641small protein activating enzyme activityMF 1e-050.00136 GO:0006627mitochondrial protein processingBP 8e-050.00136 GO:0009092homoserine metabolismBP 8e-050.00136 GO:0001308loss of chromatin silencing during replicative cell agingBP 8e-050.00136 GO:0046686response to cadmium ionBP 8e-050.00136 GO:0045332phospholipid translocationBP 8e-050.00136 GO:0005822inner plaque of spindle pole bodyCC 4e-050.00135 GO:0000112nucleotide-excision repair factor 3 complexCC 4e-050.00135 GO:0008622epsilon DNA polymerase complexCC 4e-050.00135 GO:0009096aromatic amino acid family biosynthesis, anthranilate pathwayBP 8e-050.00134 GO:0000162tryptophan biosynthesisBP 8e-050.00134 GO:0006586indolalkylamine metabolismBP 8e-050.00134 GO:0042278purine nucleoside metabolismBP 8e-050.00134 GO:0042430indole and derivative metabolismBP 8e-050.00134 GO:0006620posttranslational protein targeting to membraneBP 8e-050.00134 GO:0042434indole derivative metabolismBP 8e-050.00134 GO:0009071serine family amino acid catabolismBP 8e-050.00134 GO:0006568tryptophan metabolismBP 8e-050.00134 GO:0042435indole derivative biosynthesisBP 8e-050.00134 GO:0046219indolalkylamine biosynthesisBP 8e-050.00134 GO:0001522pseudouridine synthesisBP 8e-050.00134 GO:0006984ER-nuclear signaling pathwayBP 8e-050.00134 GO:00060771,6-beta-glucan metabolismBP 8e-050.00134 GO:0006862nucleotide transportBP 8e-050.00134 GO:0030968unfolded protein responseBP 8e-050.00134 GO:0006452translational frameshiftingBP 8e-050.00134 GO:0030008TRAPP complexCC 4e-050.00132 GO:0000136alpha-1,6-mannosyltransferase complexCC 4e-050.00132 GO:0031501mannosyltransferase complexCC 4e-050.00132 GO:0005880nuclear microtubuleCC 4e-050.00132 GO:0031206Sec complex-associated translocon complexCC 4e-050.00132 GO:0031201SNARE complexCC 4e-050.00132 GO:0007187G-protein signaling, coupled to cyclic nucleotide second messengerBP 7e-050.00132 GO:0000409regulation of transcription by galactoseBP 7e-050.00132 GO:0000411positive regulation of transcription by galactoseBP 7e-050.00132 GO:0045991positive regulation of transcription by carbon catabolitesBP 7e-050.00132 GO:0045116protein neddylationBP 7e-050.00132 GO:0007188G-protein signaling, coupled to cAMP nucleotide second messengerBP 7e-050.00132 GO:0043633modification-dependent RNA catabolismBP 7e-050.0013 GO:0018410peptide or protein carboxyl-terminal blockingBP 7e-050.0013 GO:00060781,6-beta-glucan biosynthesisBP 7e-050.0013 GO:0043634polyadenylation-dependent ncRNA catabolismBP 7e-050.0013 GO:0030071regulation of mitotic metaphase/anaphase transitionBP 7e-050.0013 GO:0007535donor selectionBP 7e-050.00129 GO:0006501C-terminal protein lipidationBP 7e-050.00129 GO:0006000fructose metabolismBP 7e-050.00127 GO:0009636response to toxinBP 7e-050.00127 GO:0045041protein import into mitochondrial intermembrane spaceBP 6e-050.00125 GO:0009086methionine biosynthesisBP 6e-050.00125 GO:0000350formation of catalytic spliceosome for second transesterification stepBP 6e-050.00125 GO:0046021regulation of transcription from RNA polymerase II promoter, mitoticBP 6e-050.00125 GO:0046466membrane lipid catabolismBP 6e-050.00125 GO:0007070negative regulation of transcription from RNA polymerase II promoter, mitoticBP 6e-050.00125 GO:0051083cotranslational protein foldingBP 6e-050.00125 GO:0005992trehalose biosynthesisBP 6e-050.00123 GO:0046351disaccharide biosynthesisBP 6e-050.00123 GO:0006635fatty acid beta-oxidationBP 6e-050.00123 GO:0016036cellular response to phosphate starvationBP 6e-050.00122 GO:0006269DNA replication, synthesis of RNA primerBP 6e-050.00122 GO:0046475glycerophospholipid catabolismBP 6e-050.00122 GO:0050793regulation of developmentBP 6e-050.00122 GO:0009395phospholipid catabolismBP 6e-050.00122 GO:0006797polyphosphate metabolismBP 6e-050.00122 GO:0006900vesicle buddingBP 6e-050.00122 GO:0006101citrate metabolismBP 6e-050.00122 GO:0006901vesicle coatingBP 6e-050.00122 GO:0000038very-long-chain fatty acid metabolismBP 6e-050.00122 GO:0009083branched chain family amino acid catabolismBP 6e-050.00122 GO:0045252oxoglutarate dehydrogenase complexCC 3e-050.00121 GO:0031902late endosome membraneCC 3e-050.00121 GO:0031207Sec62/Sec63 complexCC 3e-050.00121 GO:0009353oxoglutarate dehydrogenase complex (sensu Eukaryota)CC 3e-050.00121 GO:0005688snRNP U6CC 3e-050.00121 GO:0042719mitochondrial intermembrane space protein transporter complexCC 3e-050.00121 GO:0000817COMA complexCC 3e-050.00121 GO:0005674transcription factor TFIIF complexCC 3e-050.00121 GO:0045261proton-transporting ATP synthase complex, catalytic core F(1)CC 3e-050.00121 GO:0000275proton-transporting ATP synthase complex, catalytic core F(1) (sensu Eukaryota)CC 3e-050.00121 GO:003068690S preribosomeCC 3e-050.00121 GO:0006549isoleucine metabolismBP 5e-050.00119 GO:0000916cytokinesis, contractile ring contractionBP 5e-050.00119 GO:0006220pyrimidine nucleotide metabolismBP 5e-050.00119 GO:0006431methionyl-tRNA aminoacylationBP 5e-050.00117 GO:0016584nucleosome spacingBP 5e-050.00117 GO:0000304response to singlet oxygenBP 5e-050.00115 GO:0042375quinone cofactor metabolismBP 5e-050.00115 GO:0009113purine base biosynthesisBP 5e-050.00115 GO:0046688response to copper ionBP 5e-050.00115 GO:0046486glycerolipid metabolismBP 5e-050.00115 GO:0006638neutral lipid metabolismBP 5e-050.00115 GO:0006744ubiquinone biosynthesisBP 5e-050.00115 GO:0006641triacylglycerol metabolismBP 5e-050.00115 GO:0000338protein deneddylationBP 5e-050.00115 GO:0006743ubiquinone metabolismBP 5e-050.00115 GO:0030162regulation of proteolysisBP 5e-050.00115 GO:0045426quinone cofactor biosynthesisBP 5e-050.00115 GO:0006662glycerol ether metabolismBP 5e-050.00115 GO:0006639acylglycerol metabolismBP 5e-050.00115 GO:0005991trehalose metabolismBP 5e-050.00115 GO:0006591ornithine metabolismBP 5e-050.00115 GO:0006658phosphatidylserine metabolismBP 5e-050.00115 GO:0019321pentose metabolismBP 4e-050.00109 GO:0031118rRNA pseudouridine synthesisBP 4e-050.00109 GO:0001100negative regulation of exit from mitosisBP 4e-050.00109 GO:0042542response to hydrogen peroxideBP 4e-050.00109 GO:0000188inactivation of MAPK activityBP 4e-050.00109 GO:0006534cysteine metabolismBP 4e-050.00109 GO:0031111negative regulation of microtubule polymerization or depolymerizationBP 4e-050.00109 GO:0006720isoprenoid metabolismBP 4e-050.00109 GO:0000173inactivation of MAPK activity during osmolarity sensingBP 4e-050.00109 GO:0019541propionate metabolismBP 4e-050.00109 GO:0007135meiosis IIBP 4e-050.00109 GO:0006771riboflavin metabolismBP 4e-050.00109 GO:0006598polyamine catabolismBP 4e-050.00109 GO:0009119ribonucleoside metabolismBP 4e-050.00109 GO:0017157regulation of exocytosisBP 4e-050.00109 GO:0046839phospholipid dephosphorylationBP 4e-050.00109 GO:0030469maintenance of cell polarity (sensu Fungi)BP 4e-050.00109 GO:0030011maintenance of cell polarityBP 4e-050.00109 GO:0006448regulation of translational elongationBP 4e-050.00109 GO:0006624vacuolar protein processing or maturationBP 4e-050.00109 GO:0009231riboflavin biosynthesisBP 4e-050.00109 GO:0042402biogenic amine catabolismBP 4e-050.00109 GO:0007026negative regulation of microtubule depolymerizationBP 4e-050.00109 GO:0031114regulation of microtubule depolymerizationBP 4e-050.00109 GO:0009435NAD biosynthesisBP 4e-050.00109 GO:0046856phosphoinositide dephosphorylationBP 4e-050.00109 GO:0007019microtubule depolymerizationBP 4e-050.00109 GO:0007090regulation of S phase of mitotic cell cycleBP 4e-050.00109 GO:0008299isoprenoid biosynthesisBP 4e-050.00109 GO:0043407negative regulation of MAPK activityBP 4e-050.00109 GO:0006621protein retention in ERBP 4e-050.00109 GO:0045144meiotic sister chromatid segregationBP 4e-050.00109 GO:0006528asparagine metabolismBP 4e-050.00109 GO:0046128purine ribonucleoside metabolismBP 4e-050.00109 GO:0006013mannose metabolismBP 4e-050.00109 GO:0045334clathrin-coated endocytic vesicleCC 3e-050.00093 GO:0005769early endosomeCC 3e-050.00093 GO:0000274proton-transporting ATP synthase, stator stalk (sensu Eukaryota)CC 3e-050.00093 GO:0005960glycine cleavage complexCC 3e-050.00093 GO:0030128clathrin coat of endocytic vesicleCC 3e-050.00093 GO:0008275gamma-tubulin small complexCC 3e-050.00093 GO:0000177cytoplasmic exosome (RNase complex)CC 3e-050.00093 GO:0030123AP-3 adaptor complexCC 3e-050.00093 GO:0019774proteasome core complex, beta-subunit complex (sensu Eukaryota)CC 3e-050.00093 GO:0005787signal peptidase complexCC 3e-050.00093 GO:0000138Golgi trans cisternaCC 3e-050.00093 GO:0042555MCM complexCC 3e-050.00093 GO:0000938GARP complexCC 3e-050.00093 GO:0005662DNA replication factor A complexCC 3e-050.00093 GO:0000815ESCRT III complexCC 3e-050.00093 GO:0005956protein kinase CK2 complexCC 3e-050.00093 GO:0030688nucleolar preribosome, small subunit precursorCC 3e-050.00093 GO:0000930gamma-tubulin complexCC 3e-050.00093 GO:0005756proton-transporting ATP synthase, central stalk (sensu Eukaryota)CC 3e-050.00093 GO:0030666endocytic vesicle membraneCC 3e-050.00093 GO:0032040small subunit processomeCC 3e-050.00093 GO:0030904retromer complexCC 3e-050.00093 GO:0000818MIND complexCC 3e-050.00093 GO:0000928gamma-tubulin complex (sensu Saccharomyces)CC 3e-050.00093 GO:0030130clathrin coat of trans-Golgi network vesicleCC 3e-050.00093 GO:0017119Golgi transport complexCC 3e-050.00093 GO:0042729DASH complexCC 3e-050.00093 GO:0030689Noc complexCC 3e-050.00093 GO:0045298tubulin complexCC 3e-050.00093 GO:0031417NatC complexCC 3e-050.00093 GO:0031262Ndc80 complexCC 3e-050.00093 GO:0005784translocon complexCC 3e-050.00093 GO:0005827polar microtubuleCC 3e-050.00093 GO:0045265proton-transporting ATP synthase, stator stalkCC 3e-050.00093 GO:0005834heterotrimeric G-protein complexCC 3e-050.00093 GO:0005905coated pitCC 3e-050.00093 GO:0000814ESCRT II complexCC 3e-050.00093 GO:0043529GET complexCC 3e-050.00093 GO:0031499TRAMP complexCC 3e-050.00093 GO:0030122AP-2 adaptor complexCC 3e-050.00093 GO:0005854nascent polypeptide-associated complexCC 3e-050.00093 GO:0005952cAMP-dependent protein kinase complexCC 3e-050.00093 GO:0030015CCR4-NOT core complexCC 3e-050.00093 GO:0030897HOPS complexCC 3e-050.00093 GO:0016592Srb-mediator complexCC 3e-050.00093 GO:0045269proton-transporting ATP synthase, central stalkCC 3e-050.00093 GO:0030132clathrin coat of coated pitCC 3e-050.00093 GO:0030139endocytic vesicleCC 3e-050.00093 GO:0031314extrinsic to mitochondrial inner membraneCC 3e-050.00093 GO:0051233spindle midzoneCC 3e-050.00093 GO:0030121AP-1 adaptor complexCC 3e-050.00093 GO:0000221hydrogen-transporting ATPase V1 domainCC 3e-050.00093 GO:0030669clathrin-coated endocytic vesicle membraneCC 3e-050.00093 GO:0016602</